ID   MCF-7/S9
AC   CVCL_AS09
SY   MCF7/S9; MCF-7 subline 9
DR   cancercelllines; CVCL_AS09
DR   CancerTools; 152602
DR   ECACC; 16022530
DR   Wikidata; Q54904380
DR   Ximbio; 152602
RX   PubMed=3513694;
RX   PubMed=12732292;
CC   Group: Serum/protein free medium cell line.
CC   Population: Caucasian.
CC   Doubling time: ~44 hours, 34 hours (Note=When estradiol added in medium) (PubMed=12732292).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Discontinued: ECACC; 16022530; true.
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0031 ! MCF-7
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 02-05-16; Last updated: 19-12-24; Version: 17
//
RX   PubMed=12732292; DOI=10.1016/S0960-0760(03)00068-2;
RA   Jensen, Janne
RA   Kitlen, Jason W.
RA   Briand, Per
RA   Labrie, Fernand
RA   Lykkesfeldt, Anne E.
RT   "Effect of antiestrogens and aromatase inhibitor on basal growth of
RT   the human breast cancer cell line MCF-7 in serum-free medium.";
RL   J. Steroid Biochem. Mol. Biol. 84:469-478(2003).
//
RX   PubMed=3513694;
RA   Briand, Per
RA   Lykkesfeldt, Anne E.
RT   "Long-term cultivation of a human breast cancer cell line, MCF-7, in a
RT   chemically defined medium. Effect of estradiol.";
RL   Anticancer Res. 6:85-90(1986).
//