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Cellosaurus HCEC 1CT+7 (CVCL_AQ46)

[Text version]
Cell line name HCEC 1CT+7
Synonyms HCEC 1CT7; 1CT7
Accession CVCL_AQ46
Resource Identification Initiative To cite this cell line use: HCEC 1CT+7 (RRID:CVCL_AQ46)
Comments Karyotypic information: Has acquired a chromosome 7 trisomy.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1773; CDK4.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Omics: Genomics; Whole exome sequencing.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Cell type: Epithelial cell of colon; CL=CL_0011108.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_AQ45 (HCEC 1CT)
Sex of cell Male
Age at sampling 54Y
Category Telomerase immortalized cell line
Publications

PubMed=21472139; DOI=10.1593/neo.101580; PMCID=PMC3071083
Ly P., Eskiocak U., Kim S.B., Roig A.I., Hight S.K., Lulla D.R., Zou Y.S., Batten K.G., Wright W.E., Shay J.W.
Characterization of aneuploid populations with trisomy 7 and 20 derived from diploid human colonic epithelial cells.
Neoplasia 13:348-357(2011)

PubMed=25923178; DOI=10.1186/1471-2164-16-S1-S8; PMCID=PMC4315167
Zhang L., Kim S.B., Jia G.-X., Buhmeida A., Dallol A., Wright W.E., Fornace A.J. Jr., Al-Qahtani M., Shay J.W.
Exome sequencing of normal and isogenic transformed human colonic epithelial cells (HCECs) reveals novel genes potentially involved in the early stages of colorectal tumorigenesis.
BMC Genomics 16 Suppl. 1:S8.1-S8.8(2015)

Cross-references
Encyclopedic resources Wikidata; Q54881864
Entry history
Entry creation02-May-2016
Last entry update10-Apr-2025
Version number11