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Cellosaurus HCEC 1CT+7 (CVCL_AQ46)

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Cell line name HCEC 1CT+7
Synonyms HCEC 1CT7; 1CT7
Accession CVCL_AQ46
Resource Identification Initiative To cite this cell line use: HCEC 1CT+7 (RRID:CVCL_AQ46)
Comments Karyotypic information: Has acquired a chromosome 7 trisomy.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1773; CDK4.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Omics: Genomics; Whole exome sequencing.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Cell type: Epithelial cell of colon; CL=CL_0011108.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_AQ45 (HCEC 1CT)
Sex of cell Male
Age at sampling 54Y
Category Telomerase immortalized cell line
Publications

PubMed=21472139; DOI=10.1593/neo.101580; PMCID=PMC3071083
Peter Ly, Ugur Eskiocak, Sang Bum Kim, Andres I. Roig, Suzie K. Hight, Dypti R. Lulla, Ying S. Zou, Kimberly G. Batten, Woodring Erik Wright, Jerry W. Shay;
Characterization of aneuploid populations with trisomy 7 and 20 derived from diploid human colonic epithelial cells.
Neoplasia 13:348-357(2011)

PubMed=25923178; DOI=10.1186/1471-2164-16-S1-S8; PMCID=PMC4315167
Lu Zhang, Sang Bum Kim, Gao-Xiang Jia, Abdelbaset Buhmeida, Ashraf Dallol, Woodring Erik Wright, Albert J. Fornace Jr., Mohammed Al-Qahtani, Jerry W. Shay;
Exome sequencing of normal and isogenic transformed human colonic epithelial cells (HCECs) reveals novel genes potentially involved in the early stages of colorectal tumorigenesis.
BMC Genomics 16 Suppl. 1:S8.1-S8.8(2015)

Cross-references
Encyclopedic resources Wikidata; Q54881864
Entry history
Entry creation02-May-2016
Last entry update10-Apr-2025
Version number11