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Cellosaurus hTCEpi (CVCL_AQ44)

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Cell line name hTCEpi
Synonyms hTCE-Pi; human Telomerase-immortalized Corneal Epithelial cell line; THCE; Telomerase-immortalized Human Corneal Epithelial cells
Accession CVCL_AQ44
Secondary accession CVCL_A5RG
Resource Identification Initiative To cite this cell line use: hTCEpi (RRID:CVCL_AQ44)
Comments Part of: Human Protein Atlas, Cell Atlas panel.
Doubling time: 24-32 hours (Evercyte=CHT-045-0237).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Omics: Proteomics; Expression; Large antibody panel staining analysis.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Eye, cornea, epithelium; UBERON=UBERON_0001772.
Cell type: Epithelial cell of cornea; CL=CL_0000575.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 62Y
Category Telomerase immortalized cell line
STR profile Source(s): PubMed=29787296

Markers:
AmelogeninX,Y
CSF1PO11
D3S135817
D5S81811
D7S82011,12
D8S117912,13
D13S31711,12
D16S5399,11
D18S5112,15
D21S1132.2,33.2
FGA15,17
Penta D12,14
Penta E12,15
TH017
TPOX8,10
vWA14,17

Run an STR similarity search on this cell line
Web pages Info; HPA; -; https://www.proteinatlas.org/learn/cellines
Publications

PubMed=15671271; DOI=10.1167/iovs.04-0528
Danielle M. Robertson, Li Li, Stephen Fisher, Virginia P. Pearce, Jerry W. Shay, Woodring Erik Wright, Harrison Dwight Cavanagh, James V. Jester;
Characterization of growth and differentiation in a telomerase-immortalized human corneal epithelial cell line.
Invest. Ophthalmol. Vis. Sci. 46:470-478(2005)

PubMed=17543179; DOI=10.5555/cmj.0366-6999.120.10.p893.01
Xin-Yi Wu, Jian-Lu Gao, Mei-Yu Ren;
Expression profiles and function of Toll-like receptors in human corneal epithelia.
Chin. Med. J. 120:893-897(2007)

PubMed=21780919; DOI=10.3109/02713683.2011.582662; PMCID=PMC3149847
Danielle M. Robertson, Jerry P. Kalangara, Rebeccah B. Baucom, Walter Matthew Petroll, Harrison Dwight Cavanagh;
A reconstituted telomerase-immortalized human corneal epithelium in vivo: a pilot study.
Curr. Eye Res. 36:706-712(2011)

PubMed=29787296; DOI=10.1080/02713683.2018.1480043; PMCID=PMC6590053
Alison M. McDermott, Hasna Baidouri, Ashley M. Woodward, Wendy R. Kam, Yang Liu, Xiao-Min Chen, Jillian F. Ziemanski, Kerry Vistisen, Linda D. Hazlett, Kelly K. Nichols, Pablo Argueso, David A. Sullivan;
Short tandem repeat (STR) profiles of commonly used human ocular surface cell lines.
Curr. Eye Res. 43:1097-1101(2018)

Cross-references
Cell line collections (Providers) Evercyte; CHT-045-0237
Anatomy/cell type resources BTO; BTO_0004498
Encyclopedic resources Wikidata; Q54896606
Gene expression databases GEO; GSM7701472
GEO; GSM7701473
Entry history
Entry creation02-May-2016
Last entry update14-Aug-2025
Version number15