ID   hTCEpi
AC   CVCL_AQ44
AS   CVCL_A5RG
SY   hTCE-Pi; human Telomerase-immortalized Corneal Epithelial cell line; THCE; Telomerase-immortalized Human Corneal Epithelial cells
DR   BTO; BTO_0004498
DR   Evercyte; CHT-045-0237
DR   GEO; GSM7701472
DR   GEO; GSM7701473
DR   Wikidata; Q54896606
RX   PubMed=15671271;
RX   PubMed=17543179;
RX   PubMed=21780919;
RX   PubMed=29787296;
WW   Info; HPA; -; https://www.proteinatlas.org/learn/cellines
CC   Part of: Human Protein Atlas, Cell Atlas panel.
CC   Doubling time: 24-32 hours (Evercyte=CHT-045-0237).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Omics: Proteomics; Expression; Large antibody panel staining analysis.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Eye, cornea, epithelium; UBERON=UBERON_0001772.
CC   Cell type: Epithelial cell of cornea; CL=CL_0000575.
ST   Source(s): PubMed=29787296
ST   Amelogenin: X,Y
ST   CSF1PO: 11
ST   D13S317: 11,12
ST   D16S539: 9,11
ST   D18S51: 12,15
ST   D21S11: 32.2,33.2
ST   D3S1358: 17
ST   D5S818: 11
ST   D7S820: 11,12
ST   D8S1179: 12,13
ST   FGA: 15,17
ST   Penta D: 12,14
ST   Penta E: 12,15
ST   TH01: 7
ST   TPOX: 8,10
ST   vWA: 14,17
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   62Y
CA   Telomerase immortalized cell line
DT   Created: 02-05-16; Last updated: 10-04-25; Version: 14
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RX   PubMed=15671271; DOI=10.1167/iovs.04-0528;
RA   Robertson D.M., Li L., Fisher S., Pearce V.P., Shay J.W., Wright W.E.,
RA   Cavanagh H.D., Jester J.V.;
RT   "Characterization of growth and differentiation in a
RT   telomerase-immortalized human corneal epithelial cell line.";
RL   Invest. Ophthalmol. Vis. Sci. 46:470-478(2005).
//
RX   PubMed=17543179; DOI=10.5555/cmj.0366-6999.120.10.p893.01;
RA   Wu X.-Y., Gao J.-L., Ren M.-Y.;
RT   "Expression profiles and function of Toll-like receptors in human
RT   corneal epithelia.";
RL   Chin. Med. J. 120:893-897(2007).
//
RX   PubMed=21780919; DOI=10.3109/02713683.2011.582662; PMCID=PMC3149847;
RA   Robertson D.M., Kalangara J.P., Baucom R.B., Petroll W.M.,
RA   Cavanagh H.D.;
RT   "A reconstituted telomerase-immortalized human corneal epithelium in
RT   vivo: a pilot study.";
RL   Curr. Eye Res. 36:706-712(2011).
//
RX   PubMed=29787296; DOI=10.1080/02713683.2018.1480043; PMCID=PMC6590053;
RA   McDermott A.M., Baidouri H., Woodward A.M., Kam W.R., Liu Y., Chen X.-M.,
RA   Ziemanski J.F., Vistisen K., Hazlett L.D., Nichols K.K., Argueso P.,
RA   Sullivan D.A.;
RT   "Short tandem repeat (STR) profiles of commonly used human ocular
RT   surface cell lines.";
RL   Curr. Eye Res. 43:1097-1101(2018).
//