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Cellosaurus HC84S (CVCL_A9Y0)

[Text version]
Cell line name HC84S
Accession CVCL_A9Y0
Resource Identification Initiative To cite this cell line use: HC84S (RRID:CVCL_A9Y0)
Comments Group: Serum/protein free medium cell line.
Population: Caucasian.
Doubling time: 6-7 days (PubMed=6932031).
Derived from site: Metastatic; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Leu1488Phefs*19 (c.4464delA); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu542Lys (c.1624G>A); ClinVar=VCV000031944; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Lys340Asn (c.1020G>C); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; c.560-1G>T; ClinVar=VCV003148249; Zygosity=Homozygous; Note=Splice acceptor mutation (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0555 (T84)
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
Publications

PubMed=6932031; DOI=10.1073/pnas.77.6.3464; PMCID=PMC349637
Hiroki Murakami, Hideo Masui;
Hormonal control of human colon carcinoma cell growth in serum-free medium.
Proc. Natl. Acad. Sci. U.S.A. 77:3464-3468(1980)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A9Y0
Encyclopedic resources Wikidata; Q102114104
Entry history
Entry creation29-Oct-2020
Last entry update19-Dec-2024
Version number9