ID   HC84S
AC   CVCL_A9Y0
DR   cancercelllines; CVCL_A9Y0
DR   Wikidata; Q102114104
RX   PubMed=6932031;
CC   Group: Serum/protein free medium cell line.
CC   Population: Caucasian.
CC   Doubling time: 6-7 days (PubMed=6932031).
CC   Sequence variation: Mutation; HGNC; 583; APC; Simple; p.Leu1488Phefs*19 (c.4464delA); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu542Lys (c.1624G>A); ClinVar=VCV000031944; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6770; SMAD4; Simple; p.Lys340Asn (c.1020G>C); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; c.560-1G>T; Zygosity=Homozygous; Note=Splice acceptor mutation (from parent cell line).
CC   Derived from site: Metastatic; Lung; UBERON=UBERON_0002048.
DI   NCIt; C4349; Colon adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0555 ! T84
SX   Male
AG   72Y
CA   Cancer cell line
DT   Created: 29-10-20; Last updated: 05-10-23; Version: 8
//
RX   PubMed=6932031; DOI=10.1073/pnas.77.6.3464;
RA   Murakami H., Masui H.;
RT   "Hormonal control of human colon carcinoma cell growth in serum-free
RT   medium.";
RL   Proc. Natl. Acad. Sci. U.S.A. 77:3464-3468(1980).
//