Cellosaurus MOC-L4 (CVCL_A9X6)
| Cell line name | MOC-L4 |
|---|---|
| Synonyms | Mouse Oral Carcinoma-Line 4 |
| Accession | CVCL_A9X6 |
| Resource Identification Initiative | To cite this cell line use: MOC-L4 (RRID:CVCL_A9X6) |
| Comments | Characteristics: Compared to other MOC-L cell lines, MOC-L4 is the least aggressive, has the lowest proliferation rate, invasion ability and colony formation ability. It has high migration competence and the highest tolerance to CDDP treatment (PubMed=30922255). Doubling time: 29.3 hours (PubMed=30922255). Genetic integration: Method=Transgenic mouse; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:2676887; Mir211. Transformant: ChEBI; CHEBI_16907; 4-nitroquinoline N-oxide (4NQO). Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723. |
| Disease | Squamous cell carcinoma of the mouse oral cavity (NCIt: C23049) |
| Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 K14-EGFP-miR-211 transgenic. |
| Sex of cell | Sex unspecified |
| Age at sampling | 22-28W |
| Category | Cancer cell line |
| Publications | PubMed=30922255; DOI=10.1186/s12885-019-5486-7; PMCID=PMC6440159 |
| Cross-references | |
| Cell line collections (Providers) | ABM; T8049
BCRC; 60619 |
| Encyclopedic resources | Wikidata; Q102114551 |
| Entry history | |
| Entry creation | 29-Oct-2020 |
| Last entry update | 10-Apr-2025 |
| Version number | 7 |