ID   MOC-L4
AC   CVCL_A9X6
SY   Mouse Oral Carcinoma-Line 4
DR   ABM; T8049
DR   BCRC; 60619
DR   Wikidata; Q102114551
RX   PubMed=30922255;
CC   Characteristics: Compared to other MOC-L cell lines, MOC-L4 is the least aggressive, has the lowest proliferation rate, invasion ability and colony formation ability. It has high migration competence and the highest tolerance to CDDP treatment (PubMed=30922255).
CC   Doubling time: 29.3 hours (PubMed=30922255).
CC   Genetic integration: Method=Transgenic mouse; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:2676887; Mir211.
CC   Transformant: ChEBI; CHEBI_16907; 4-nitroquinoline N-oxide (4NQO).
CC   Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
CC   Breed/subspecies: C57BL/6 K14-EGFP-miR-211 transgenic.
DI   NCIt; C23049; Squamous cell carcinoma of the mouse oral cavity
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   22-28W
CA   Cancer cell line
DT   Created: 29-10-20; Last updated: 10-04-25; Version: 7
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RX   PubMed=30922255; DOI=10.1186/s12885-019-5486-7; PMCID=PMC6440159;
RA   Chen, Yi-Fen
RA   Liu, Chung-Ji
RA   Lin, Li-Han
RA   Chou, Chung-Hsien
RA   Yeh, Li-Yin
RA   Lin, Shu-Chun
RA   Chang, Kuo-Wei
RT   "Establishing of mouse oral carcinoma cell lines derived from
RT   transgenic mice and their use as syngeneic tumorigenesis models.";
RL   BMC Cancer 19:281.1-281.11(2019).
//