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Cellosaurus BPS Bioscience A-549 NF-kappaB-driven luciferase reporter (CVCL_A9P0)

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Cell line name BPS Bioscience A-549 NF-kappaB-driven luciferase reporter
Synonyms NF-KappaB reporter (Luc)-A549; NF-kappaB luciferase reporter A549
Accession CVCL_A9P0
Resource Identification Initiative To cite this cell line use: BPS Bioscience A-549 NF-kappaB-driven luciferase reporter (RRID:CVCL_A9P0)
Comments Population: Caucasian.
Characteristics: Expression of the luciferase reporter gene is driven by four copies of the NF-kappaB response element located upstream of a minimal TATA promoter (BPS Bioscience=60625).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Web pages Provider; BPS Bioscience; 60625; https://bpsbioscience.com/nf-kb-reporter-luc-a549-recombinant-stable-cell-line-60625
Cross-references
Cell line databases/resources cancercelllines; CVCL_A9P0
Encyclopedic resources Wikidata; Q102114592
Entry history
Entry creation29-Oct-2020
Last entry update14-Aug-2025
Version number11