ID   BPS Bioscience A-549 NF-kappaB-driven luciferase reporter
AC   CVCL_A9P0
SY   NF-KappaB reporter (Luc)-A549; NF-kappaB luciferase reporter A549
DR   cancercelllines; CVCL_A9P0
DR   Wikidata; Q102114592
WW   Provider; BPS Bioscience; 60625; https://bpsbioscience.com/nf-kb-reporter-luc-a549-recombinant-stable-cell-line-60625
CC   Population: Caucasian.
CC   Characteristics: Expression of the luciferase reporter gene is driven by four copies of the NF-kappaB response element located upstream of a minimal TATA promoter (BPS Bioscience=60625).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0023 ! A-549
SX   Male
AG   58Y
CA   Cancer cell line
DT   Created: 29-10-20; Last updated: 10-04-25; Version: 10
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