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Cellosaurus IPEC-J2 rMDR1a (CVCL_A9M7)

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Cell line name IPEC-J2 rMDR1a
Accession CVCL_A9M7
Resource Identification Initiative To cite this cell line use: IPEC-J2 rMDR1a (RRID:CVCL_A9M7)
Comments Characteristics: Can be used to screen drug compounds for interactions with rat efflux pump P-glycoprotein (P-gp).
Transfected with: RGD; 619951; Abcb1a.
Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Small intestine, jejunum; UBERON=UBERON_0002115.
Cell type: Enterocyte; CL=CL_0000584.
Species of origin Sus scrofa (Pig) (NCBI Taxonomy: 9823)
Hierarchy Parent: CVCL_2246 (IPEC-J2)
Sex of cell Sex unspecified
Age at sampling <1D
Category Spontaneously immortalized cell line

PubMed=32708885; DOI=10.3390/pharmaceutics12070673
Saaby L., Trasborg J., Rasmussen M.A., Holst B., Brodin B.
IPEC-J2 rMdr1a, a new cell line with functional expression of rat P-glycoprotein encoded by rat Mdr1a for drug screening purposes.
Pharmaceutics 12:673.1-673.17(2020)

Encyclopedic resources Wikidata; Q102114239
Entry history
Entry creation29-Oct-2020
Last entry update29-Jun-2023
Version number7