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Cellosaurus HepG2-CYP3A29 (CVCL_A9JD)

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Cell line name HepG2-CYP3A29
Accession CVCL_A9JD
Resource Identification Initiative To cite this cell line use: HepG2-CYP3A29 (RRID:CVCL_A9JD)
Comments Population: Caucasian.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=VGNC; VGNC:103556; Pig CYP3A29.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

CLPUB00644
Zheng-Kai Xue, Hong Wei, Hai-Tao Shang, Bin Ye;
Establishment of a HepG2 cell line stably expressing the CYP3A29 isoenzyme and identification of its nifedipine metabolic activity.
Zhongguo Ren Shou Gong Huan Bing Xue Bao 25:640-644(2009)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A9JD
Encyclopedic resources Wikidata; Q108820459
Entry history
Entry creation23-Sep-2021
Last entry update14-Aug-2025
Version number9