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Cellosaurus MKN45/DR (CVCL_A9J7)

[Text version]
Cell line name MKN45/DR
Synonyms MKN-45/DR
Accession CVCL_A9J7
Resource Identification Initiative To cite this cell line use: MKN45/DR (RRID:CVCL_A9J7)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI_46345; 5-fluorouracil (5-FU).
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Heterozygous (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0434 (MKN45)
Sex of cell Female
Age at sampling 62Y
Category Cancer cell line
Publications

DOI=10.1016/j.procbio.2020.01.033
Farhad Pouremamali, Farhad Jeddi, Nasser Samadi;
Nrf2-ME-1 axis is associated with 5-FU resistance in gastric cancer cell line.
Process Biochem. 114:174-184(2022)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A9J7
Encyclopedic resources Wikidata; Q102114543
Entry history
Entry creation29-Oct-2020
Last entry update19-Dec-2024
Version number7