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Cellosaurus Daoy-luc2-tdT (CVCL_A9DF)

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Cell line name Daoy-luc2-tdT
Accession CVCL_A9DF
Resource Identification Initiative To cite this cell line use: Daoy-luc2-tdT (RRID:CVCL_A9DF)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=FPbase; PGG5S; tdTomato (Note=Bright red fluorescent protein derived from drFP583 (DsRed)).
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase (Note=With optimized codon usage for mammalian expression = Luc2).
Derived from site: In situ; Brain, posterior fossa; UBERON=UBERON_0008788.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys242Phe (c.725G>T); ClinVar=VCV000376578; Zygosity=Homozygous (from parent cell line).
Disease Medulloblastoma, SHH-activated, TP53-mutant (NCIt: C129442)
Medulloblastoma (ORDO: Orphanet_616)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1167 (Daoy)
Sex of cell Male
Age at sampling 4Y
Category Cancer cell line
STR profile Source(s): CCRID=1101HUM-PUMC000814

Markers:
AmelogeninX
CSF1PO11
D2S133816,17
D3S135815
D5S81811,13
D6S104312
D7S8208,10
D8S117913,15
D12S39120
D13S31713,14
D16S53910
D18S5112
D19S43314,14.2
D21S1129,31.2
FGA23
Penta E7,11
TH019
TPOX8,10
vWA14,20

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Cross-references
Cell line databases/resources cancercelllines; CVCL_A9DF
CCRID; 1101HUM-PUMC000814
Encyclopedic resources Wikidata; Q108820134
Entry history
Entry creation23-Sep-2021
Last entry update14-Aug-2025
Version number11