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Cellosaurus LT97 (CVCL_A9BJ)

[Text version]
Cell line name LT97
Synonyms LT97-1
Accession CVCL_A9BJ
Resource Identification Initiative To cite this cell line use: LT97 (RRID:CVCL_A9BJ)
Comments Characteristics: Contains 2 subpopulations of cells, one CD44+, the other CD44- (PubMed=17708598).
Doubling time: ~96 hours (DOI=10.25365/thesis.6275).
Miscellaneous: STR profile mentioned in PubMed=27996158 but obtained from personal communication of Schlormann, Wiebke.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
Disease Colorectal adenoma (NCIt: C5673)
Familial adenomatous polyposis (NCIt: C3339)
Familial adenomatous polyposis (ORDO: Orphanet_733)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_D5XV (LT97-2)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=27996158

Markers:
AmelogeninX
CSF1PO8,11
D5S81811
D7S8208,12
D13S31711,13
D16S53911
TH017,9.3
TPOX8,11
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=12204677; DOI=10.1016/S0959-8049(02)00158-2
Maria Richter, Daniela Jurek, Fritz Wrba, Klaus Kaserer, Gabriele Wurzer, Judith Karner-Hanusch, Brigitte Marian;
Cells obtained from colorectal microadenomas mirror early premalignant growth patterns in vitro.
Eur. J. Cancer 38:1937-1945(2002)

PubMed=12714179; DOI=10.1016/S0027-5107(03)00012-5
Anja Schaeferhenrich, Gabriele Beyer-Sehlmeyer, Grit Festag, Alma Kuechler, Natja Haag, Anja Weise, Thomas Liehr, Uwe Claussen, Brigitte Marian, Wolfgang Sendt, Johannes Scheele, Beatrice Louise Pool-Zobel;
Human adenoma cells are highly susceptible to the genotoxic action of 4-hydroxy-2-nonenal.
Mutat. Res. 526:19-32(2003)

PubMed=17708598; DOI=10.1002/path.2220
Axel Schulenburg, P. Cech, Irene Herbacek, Brigitte Marian, Fritz Wrba, Peter Valent, Herbert Ulrich-Pur;
CD44-positive colorectal adenoma cells express the potential stem cell markers musashi antigen (msi1) and ephrin B2 receptor (EphB2).
J. Pathol. 213:152-160(2007)

DOI=10.25365/thesis.6275
Inga Koneczny;
Investigating a model cell line for tumour stem cells in colorectal cancer.
Thesis MSc (2009); University of Vienna; Vienna; Austria

PubMed=27996158; DOI=10.1002/mc.22606
Wiebke Schlormann, Julia Lamberty, Stefan Lorkowski, Diana Ludwig, Henning Mothes, Christian Saupe, Michael Glei;
Chemopreventive potential of in vitro fermented nuts in LT97 colon adenoma and primary epithelial colon cells.
Mol. Carcinog. 56:1461-1471(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A9BJ
Encyclopedic resources Wikidata; Q108820805
Polymorphism and mutation databases IARC_TP53; 25023
Entry history
Entry creation23-Sep-2021
Last entry update19-Dec-2024
Version number9