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Cellosaurus COS-33 (CVCL_A8S2)

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Cell line name COS-33
Accession CVCL_A8S2
Resource Identification Initiative To cite this cell line use: COS-33 (RRID:CVCL_A8S2)
Comments Population: Caucasian.
Characteristics: Established from a patient-derived xenograft in its third passage (OS-33).
Derived from site: In situ; Bone, humerus; UBERON=UBERON_0000976.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Unexplicit; Ex8-9del; Zygosity=Homozygous (PubMed=32676162).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 7Y
Category Cancer cell line
Publications

PubMed=32676162; DOI=10.18632/oncotarget.27611; PMCID=PMC7343631
Ashley VanCleave, Mykayla Palmer, Fang Fang, Haydee Torres, Tania Rodezno, Qi-Lin Li, Kirby Fuglsby, Claire Evans, Yohannes Afeworki Tecleab, Alan Ross, Pulivarthi H. Rao ...Show all 15 authors... , Patricia Crotwell Leiferman, Si-Yuan Zheng, Peter J. Houghton, Jian-Ning Tao; Show fewer authors
Development and characterization of the novel human osteosarcoma cell line COS-33 with sustained activation of the mTOR pathway.
Oncotarget 11:2597-2610(2020)

Cross-references
Encyclopedic resources Wikidata; Q102113711
Entry history
Entry creation29-Oct-2020
Last entry update19-Dec-2024
Version number6