ID   COS-33
AC   CVCL_A8S2
DR   Wikidata; Q102113711
RX   PubMed=32676162;
CC   Population: Caucasian.
CC   Characteristics: Established from a patient-derived xenograft in its third passage (OS-33).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Unexplicit; Ex8-9del; Zygosity=Homozygous (PubMed=32676162).
CC   Derived from site: In situ; Bone, humerus; UBERON=UBERON_0000976.
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   7Y
CA   Cancer cell line
DT   Created: 29-10-20; Last updated: 19-12-24; Version: 6
//
RX   PubMed=32676162; DOI=10.18632/oncotarget.27611; PMCID=PMC7343631;
RA   VanCleave A., Palmer M., Fang F., Torres H., Rodezno T., Li Q.-L.,
RA   Fuglsby K., Evans C., Afeworki Tecleab Y., Ross A., Rao P.H.,
RA   Leiferman P.C., Zheng S.-Y., Houghton P.J., Tao J.-N.;
RT   "Development and characterization of the novel human osteosarcoma cell
RT   line COS-33 with sustained activation of the mTOR pathway.";
RL   Oncotarget 11:2597-2610(2020).
//