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Cellosaurus MTSV1-7 HB2-neo (CVCL_A8S0)

[Text version]
Cell line name MTSV1-7 HB2-neo
Synonyms HB2-neo; HB2 neo
Accession CVCL_A8S0
Resource Identification Initiative To cite this cell line use: MTSV1-7 HB2-neo (RRID:CVCL_A8S0)
Comments Characteristics: Control cell line for MTSV1-7 HB2-Erb-B2 (Cellosaurus=CVCL_A8R8) and MTSV1-7 HB2-Ras (Cellosaurus=CVCL_A8R9) (PubMed=8887648).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Cell type: Luminal epithelial cell; CL=CL_0002326.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2261 (MTSV1-7 HB2)
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=8887648; DOI=10.1128/mcb.16.11.6178; PMCID=PMC231621
Ye J.-P., Xu R.-H., Taylor-Papadimitriou J., Pitha P.M.
Sp1 binding plays a critical role in Erb-B2- and v-ras-mediated downregulation of alpha2-integrin expression in human mammary epithelial cells.
Mol. Cell. Biol. 16:6178-6189(1996)

CLPUB00571
Alford D.J.
Morphogenesis of human mammary epithelial cells in vitro.
Thesis PhD (1997); University College London; London; United Kingdom

PubMed=9443900; DOI=10.1242/jcs.111.4.521
Alford D.J., Baeckstrom D., Geyp M., Pitha P.M., Taylor-Papadimitriou J.
Integrin-matrix interactions affect the form of the structures developing from human mammary epithelial cells in collagen or fibrin gels.
J. Cell Sci. 111:521-532(1998)

Cross-references
Encyclopedic resources Wikidata; Q102114564
Entry history
Entry creation29-Oct-2020
Last entry update19-Dec-2024
Version number7