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Cellosaurus MTSV1-7 HB2-Erb-B2 (CVCL_A8R8)

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Cell line name MTSV1-7 HB2-Erb-B2
Synonyms HB2-Erb-B2
Accession CVCL_A8R8
Resource Identification Initiative To cite this cell line use: MTSV1-7 HB2-Erb-B2 (RRID:CVCL_A8R8)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3430; ERBB2.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Cell type: Luminal epithelial cell; CL=CL_0002326.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2261 (MTSV1-7 HB2)
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=8887648; DOI=10.1128/mcb.16.11.6178; PMCID=PMC231621
Jian-Ping Ye, Ruo-Hui Xu, Joyce Taylor-Papadimitriou, Paula M. Pitha;
Sp1 binding plays a critical role in Erb-B2- and v-ras-mediated downregulation of alpha2-integrin expression in human mammary epithelial cells.
Mol. Cell. Biol. 16:6178-6189(1996)

Cross-references
Encyclopedic resources Wikidata; Q102114562
Entry history
Entry creation29-Oct-2020
Last entry update14-Aug-2025
Version number8