Cellosaurus cell line LCSBi006-A (CVCL

Cross-references
Cell line name	LCSBi006-A
Synonyms	ND34267-LRRK2/PARK8-G2019S-clone 8; ND34267-LRRK2-clone 8; ND34267-clone 8; ND34267-8
Accession	CVCL_A8MD
Resource Identification Initiative	To cite this cell line use: LCSBi006-A (RRID:CVCL_A8MD)
Comments	From: Luxembourg Centre for Systems Biomedicine; Belvaux; Luxembourg. Population: Caucasian. Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:18618; LRRK2; Simple; p.Gly2019Ser (c.6055G>A); ClinVar=VCV000001940; Zygosity=Heterozygous (PubMed=34736041).
Disease	Parkinson disease 8, autosomal dominant (NCIt: C198605) Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_EZ01 (ND34267)
Sex of cell	Male
Age at sampling	63Y
Category	Induced pluripotent stem cell
Publications	PubMed=34736041; DOI=10.1016/j.scr.2021.102569 Gabriela Novak, Steven Finkbeiner, Gaia Skibinski, Alexander Skupin; Generation of two human induced pluripotent stem cell lines from fibroblasts of unrelated Parkinson's patients carrying the G2019S mutation in the LRRK2 gene (LCSBi005, LCSBi006). Stem Cell Res. 57:102569-102569(2021)
Cell line databases/resources	hPSCreg; LCSBi006-A
Biological sample resources	BioSamples; SAMEA10585991
Encyclopedic resources	Wikidata; Q108820777
Entry history
Entry creation	23-Sep-2021
Last entry update	19-Dec-2024
Version number	6