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Cellosaurus WM793-P2N1 (CVCL_A803)

[Text version]
Cell line name WM793-P2N1
Synonyms 793-P2-N1
Accession CVCL_A803
Resource Identification Initiative To cite this cell line use: WM793-P2N1 (RRID:CVCL_A803)
Comments Population: Caucasian.
Characteristics: Established after 2 passages of WM793 co-injected with Matrigel into nude mice.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1773; CDK4; Simple; p.Lys22Gln (c.64A>C); ClinVar=VCV000485487; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Trp274Ter (c.821G>A); ClinVar=VCV001762511; Zygosity=Heterozygous (from parent cell line).
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_8787 (WM793)
Sex of cell Male
Age at sampling 37Y
Category Cancer cell line
Publications

PubMed=8160777; PMCID=PMC1887247
Hiroaki Kobayashi, Shan Man, John R. MacDougall, Charles H. Graham, Chao Lu, Robert S. Kerbel;
Variant sublines of early-stage human melanomas selected for tumorigenicity in nude mice express a multicytokine-resistant phenotype.
Am. J. Pathol. 144:776-786(1994)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A803
Encyclopedic resources Wikidata; Q54994316
Experimental variables resources EFO; EFO_0002875
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number15