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Cellosaurus A549-hACE2 (HA-FLAG) (CVCL_A7UW)

[Text version]
Cell line name A549-hACE2 (HA-FLAG)
Accession CVCL_A7UW
Resource Identification Initiative To cite this cell line use: A549-hACE2 (HA-FLAG) (RRID:CVCL_A7UW)
Comments Group: SARS-CoV-2 research cell line.
From: Garcia-Sastre A.; The Icahn School of Medicine at Mount Sinai Medical School; New York; USA.
Population: Caucasian.
Characteristics: Expresses ACE2 with C-terminal HA and FLAG tags under the control the CMV promoter (BEI_Resources=NR-53522).
Transfected with: HGNC; 13557; ACE2.
Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Cell line collections (Providers) BEI_Resources; NR-53522
Cell line databases/resources cancercelllines; CVCL_A7UW
Encyclopedic resources Wikidata; Q107113336
Entry history
Entry creation20-May-2021
Last entry update05-Oct-2023
Version number6