ID   A549-hACE2 (HA-FLAG)
AC   CVCL_A7UW
DR   BEI_Resources; NR-53522
DR   cancercelllines; CVCL_A7UW
DR   Wikidata; Q107113336
CC   Group: SARS-CoV-2 research cell line.
CC   From: Garcia-Sastre, Adolfo; The Icahn School of Medicine at Mount Sinai Medical School; New York; USA.
CC   Population: Caucasian.
CC   Characteristics: Expresses ACE2 with C-terminal HA and FLAG tags under the control the CMV promoter (BEI_Resources=NR-53522).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:13557; ACE2.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0023 ! A-549
SX   Male
AG   58Y
CA   Cancer cell line
DT   Created: 20-05-21; Last updated: 19-12-24; Version: 8
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