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Cellosaurus Vero-Luc2p (CVCL_A7UI)

[Text version]
Cell line name Vero-Luc2p
Accession CVCL_A7UI
Resource Identification Initiative To cite this cell line use: Vero-Luc2p (RRID:CVCL_A7UI)
Comments Group: Non-human primate cell line.
Biotechnology: Used in a quantitative and sensitive luciferase-based assay for bacterial toxins that inhibit protein synthesis (PubMed=20585113).
Characteristics: Stably expresses luciferase Luc2p which is tagged with a PEST sequence which promotes rapid turnover. Therefore, luciferase activity reflects the current level of protein synthesis (PubMed=20585113).
Characteristics: Transduced with a Luc2P-IRES-eGFP construct.
Transfected with: UniProtKB; P08659; Firefly luciferase (with optimized codon usage for mammalian expression).
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Derived from site: In situ; Kidney, epithelium; UBERON=UBERON_0004819.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus) (NCBI Taxonomy: 60711)
Hierarchy Parent: CVCL_0059 (Vero)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line

PubMed=20585113; DOI=10.1128/AAC.01783-09
McGannon C.M., Fuller C.A., Weiss A.A.
Different classes of antibiotics differentially influence shiga toxin production.
Antimicrob. Agents Chemother. 54:3790-3798(2010)

Cell line collections (Providers) BEI_Resources; NR-10385
Encyclopedic resources Wikidata; Q107117399
Entry history
Entry creation20-May-2021
Last entry update05-Oct-2023
Version number5