Cellosaurus Vero-Luc2p (CVCL_A7UI)
| Cell line name | Vero-Luc2p |
|---|---|
| Accession | CVCL_A7UI |
| Resource Identification Initiative | To cite this cell line use: Vero-Luc2p (RRID:CVCL_A7UI) |
| Comments | Group: Non-human primate cell line. Biotechnology: Used in a quantitative and sensitive luciferase-based assay for bacterial toxins that inhibit protein synthesis (PubMed=20585113). Characteristics: Stably expresses luciferase Luc2p which is tagged with a PEST sequence which promotes rapid turnover. Therefore, luciferase activity reflects the current level of protein synthesis (PubMed=20585113). Characteristics: Transduced with a Luc2P-IRES-eGFP construct. Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase (Note=With optimized codon usage for mammalian expression). Derived from site: In situ; Kidney, epithelium; UBERON=UBERON_0004819. Cell type: Epithelial cell of kidney; CL=CL_0002518. |
| Species of origin | Chlorocebus sabaeus (Green monkey) (Simia sabaea) (NCBI Taxonomy: 60711) |
| Hierarchy | Parent: CVCL_0059 (Vero) |
| Sex of cell | Female |
| Age at sampling | Adult |
| Category | Spontaneously immortalized cell line |
| Publications | PubMed=20585113; DOI=10.1128/AAC.01783-09; PMCID=PMC2935008 |
| Cross-references | |
| Cell line collections (Providers) | BEI_Resources; NR-10385 |
| Encyclopedic resources | Wikidata; Q107117399 |
| Entry history | |
| Entry creation | 20-May-2021 |
| Last entry update | 10-Apr-2025 |
| Version number | 7 |