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Cellosaurus UT-SCC-54C (CVCL_A7DW)

[Text version]
Cell line name UT-SCC-54C
Synonyms University of Turku-Squamous Cell Carcinoma-54C
Accession CVCL_A7DW
Resource Identification Initiative To cite this cell line use: UT-SCC-54C (RRID:CVCL_A7DW)
Comments Omics: Genomics; Whole exome sequencing.
Caution: UT-SCC-54A, UT-SCC-54B and UT-SCC-54C are supposed to originate from the same patient but the STR profile of UT-SCC-54C is totally different from that of the two other cell lines.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Disease Buccal mucosa squamous cell carcinoma (NCIt: C4040)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_7863 ! UT-SCC-54A
CVCL_7864 ! UT-SCC-54B
Sex of cell Female
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): PubMed=30135316

Markers:
AmelogeninX
CSF1PO7,11
D2S133816
D3S135812,19
D5S81810,11
D7S82011,12
D8S117912,14
D13S31711,12
D16S53911,13
D18S5116,17
D19S43312,13
D21S1129,30
FGA18,23
TH018,9
TPOX8
vWA16,22

Run an STR similarity search on this cell line
Publications

PubMed=30135316; DOI=10.1172/jci.insight.122204; PMCID=PMC6141174
Stephen M.F. Jamieson, Peter Tsai, Maria K. Kondratyev, Pratha Budhani, Arthur Liu, Neil N. Senzer, E. Gabriela Chiorean, Shadia I. Jalal, John Joseph Nemunaitis, Dennis Kee, Avik Shome ...Show all 35 authors... , Way W. Wong, Dan Li, Nooriyah Poonawala-Lohani, Purvi M. Kakadia, Nicholas S. Knowlton, Courtney R.H. Lynch, Cho R. Hong, Tet Woo Lee, Reidar Grenman, Laura Caporiccio, Trevor David McKee, Mark Zaidi, Sehrish Butt, Andrew M.J. Macann, Nicholas P. McIvor, John M. Chaplin, Kevin O. Hicks, Stefan Klaus Bohlander, Bradly G. Wouters, Charles P. Hart, Cristin Gregor Print, William R. Wilson, Michael A. Curran, Francis W. Hunter; Show fewer authors
Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma.
JCI Insight 3:e122204.1-e122204.19(2018)

DOI=10.1158/1538-7445.AM2020-507
Maria K. Kondratyev, Aleksandra Pesic, Anna Dvorkin-Sheva, Troy Ketela, Jason Moffat, Marianne Koritzinsky, Bradly G. Wouters;
Repurposing of FDA approved drugs for treatment of metastatic HNSCC.
Cancer Res. 80 Suppl. 16:507-507(2020)

Cross-references
Encyclopedic resources Wikidata; Q107117367
Entry history
Entry creation20-May-2021
Last entry update10-Apr-2025
Version number6