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Cellosaurus M14-A (CVCL_A779)

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Cell line name M14-A
Synonyms M14-ascitic form
Accession CVCL_A779
Resource Identification Initiative To cite this cell line use: M14-A (RRID:CVCL_A779)
Comments Population: Caucasian.
Derived from site: Metastatic; Right buttock, hypodermis; UBERON=UBERON_0013691+UBERON_0002072.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; c.150+2T>C (IVS1+2T>C); ClinVar=VCV000406712; Zygosity=Heterozygous; Note=Splice donor mutation (from parent cell line).
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; c.455insCdel26; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly266Glu (c.797G>A); ClinVar=VCV000161516; Zygosity=Heterozygous (from parent cell line).
Disease Amelanotic melanoma (NCIt: C3802)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1395 (M14)
Sex of cell Male
Age at sampling 33Y
Category Cancer cell line
Publications

PubMed=6470027; DOI=10.1007/BF00402467
Mitsuo Katano, Romaine Edward Saxton, Alistair J. Cochran, Reiko F. Irie;
Establishment of an ascitic human melanoma cell line that metastasizes to lung and liver in nude mice.
J. Cancer Res. Clin. Oncol. 108:197-203(1984)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A779
Encyclopedic resources Wikidata; Q54903472
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number22