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Cellosaurus CHO hAQP4-M23 (CVCL_A6YT)

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Cell line name CHO hAQP4-M23
Accession CVCL_A6YT
Resource Identification Initiative To cite this cell line use: CHO hAQP4-M23 (RRID:CVCL_A6YT)
Comments Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:637; AQP4 (Note=Isoform M23).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0214 (CHO-K1)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=23746426; DOI=10.1016/j.jneuroim.2013.03.003
Kaori Miyazaki-Komine, Yoichiro Abe, Hiroko Iwanari, Yota Suzuki, Takahiro Kikuchi, Takashi Ito, Jungo Kato, Osamu Kusano-Arai, Toshiyuki Takahashi, Shuhei Nishiyama, Hiroko Ikeshima-Kataoka, Shoji Tsuji, Takeshi Arimitsu ...Show all 19 authors... , Yasuhiro Kato, Toshiko Sakihama, Yoshiaki Toyama, Kazuo Fujihara, Takao Hamakubo, Masato Yasui; Show fewer authors
Establishment of monoclonal antibodies against the extracellular domain that block binding of NMO-IgG to AQP4.
J. Neuroimmunol. 260:107-116(2013)

PubMed=26398585; DOI=10.1111/bph.13340; PMCID=PMC4813391
Kaori Miyazaki-Komine, Yoshiki Takai, Ping Huang, Osamu Kusano-Arai, Hiroko Iwanari, Tatsuro Misu, Katsushi Koda, Katsuyuki Mitomo, Toshiko Sakihama, Yoshiaki Toyama, Kazuo Fujihara, Takao Hamakubo, Masato Yasui ...Show all 14 authors... , Yoichiro Abe; Show fewer authors
High avidity chimeric monoclonal antibodies against the extracellular domains of human aquaporin-4 competing with the neuromyelitis optica autoantibody, NMO-IgG.
Br. J. Pharmacol. 173:103-114(2016)

Cross-references
Encyclopedic resources Wikidata; Q107114655
Entry history
Entry creation20-May-2021
Last entry update14-Aug-2025
Version number9