ID   CHO hAQP4-M23
AC   CVCL_A6YT
DR   Wikidata; Q107114655
RX   PubMed=23746426;
RX   PubMed=26398585;
CC   Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:637; AQP4 (Note=Isoform M23).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_0214 ! CHO-K1
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 20-05-21; Last updated: 10-04-25; Version: 8
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RX   PubMed=23746426; DOI=10.1016/j.jneuroim.2013.03.003;
RA   Miyazaki-Komine K., Abe Y., Iwanari H., Suzuki Y., Kikuchi T., Ito T.,
RA   Kato J., Kusano-Arai O., Takahashi T., Nishiyama S.,
RA   Ikeshima-Kataoka H., Tsuji S., Arimitsu T., Kato Y., Sakihama T.,
RA   Toyama Y., Fujihara K., Hamakubo T., Yasui M.;
RT   "Establishment of monoclonal antibodies against the extracellular
RT   domain that block binding of NMO-IgG to AQP4.";
RL   J. Neuroimmunol. 260:107-116(2013).
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RX   PubMed=26398585; DOI=10.1111/bph.13340; PMCID=PMC4813391;
RA   Miyazaki-Komine K., Takai Y., Huang P., Kusano-Arai O., Iwanari H.,
RA   Misu T., Koda K., Mitomo K., Sakihama T., Toyama Y., Fujihara K.,
RA   Hamakubo T., Yasui M., Abe Y.;
RT   "High avidity chimeric monoclonal antibodies against the extracellular
RT   domains of human aquaporin-4 competing with the neuromyelitis optica
RT   autoantibody, NMO-IgG.";
RL   Br. J. Pharmacol. 173:103-114(2016).
//