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Cellosaurus U2OS TBK1 KO (CVCL_A6LQ)

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Cell line name U2OS TBK1 KO
Accession CVCL_A6LQ
Resource Identification Initiative To cite this cell line use: U2OS TBK1 KO (RRID:CVCL_A6LQ)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:11584; TBK1.
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=36415206; DOI=10.12688/f1000research.124632.2; PMCID=PMC9647147
Walaa Alshafie, Maryam Fotouhi, Irina Shlaifer, Riham Ayoubi, Aled Morgan Edwards, Thomas M. Durcan, Peter Scott McPherson, Carl Laflamme;
Identification of highly specific antibodies for serine/threonine-protein kinase TBK1 for use in immunoblot, immunoprecipitation and immunofluorescence.
F1000Research 11:977.1-977.14(2022)

Cross-references
Encyclopedic resources Wikidata; Q107117179
Entry history
Entry creation20-May-2021
Last entry update19-Dec-2024
Version number8