ID   U2OS TBK1 KO
AC   CVCL_A6LQ
DR   Wikidata; Q107117179
RX   PubMed=36415206;
CC   Population: Caucasian.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; 11584; TBK1.
CC   Sequence variation: Mutation; HGNC; 9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0042 ! U2OS
SX   Female
AG   15Y
CA   Cancer cell line
DT   Created: 20-05-21; Last updated: 05-10-23; Version: 7
//
RX   PubMed=36415206; DOI=10.12688/f1000research.124632.1;
RA   Alshafie W., Fotouhi M., Shlaifer I., Ayoubi R., Edwards A.M.,
RA   Durcan T.M., McPherson P.S., Laflamme C.;
RT   "Identification of highly specific antibodies for
RT   serine/threonine-protein kinase TBK1 for use in immunoblot,
RT   immunoprecipitation and immunofluorescence.";
RL   F1000Research 11:977.1-977.14(2022).
//