Cellosaurus logo
expasy logo

Cellosaurus FRTL-5/T (CVCL_A6IJ)

[Text version]
Cell line name FRTL-5/T
Accession CVCL_A6IJ
Resource Identification Initiative To cite this cell line use: FRTL-5/T (RRID:CVCL_A6IJ)
Comments Characteristics: Established from tumor tissue of a xenograft obtained by subcutaneous injection of FRTL-5 in C3H nu/nu nude mice (PubMed=1694496).
Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Fischer 344; RS=RS_0000215.
Hierarchy Parent: CVCL_0265 (FRTL-5)
Children:
CVCL_A6IK (FRTL-5/TA)CVCL_A6IL (FRTL-5/TP)
Sex of cell Sex unspecified
Age at sampling 6W
Category Transformed cell line
Publications

PubMed=1694496; DOI=10.1210/endo-127-1-419
Ferry A. Ossendorp, Peter F. Bruning, Ed M.D. Schuuring, Jacqueline A.M. van den Brink, Daan van der Heide, Jan J.M. de Vijlder, Tjerk W.A. de Bruin;
Thyrotropin dependent and independent thyroid cell lines selected from FRTL-5 derived tumors grown in nude mice.
Endocrinology 127:419-430(1990)

PubMed=8761378; DOI=10.1038/bjc.1996.409; PMCID=PMC2074668
Carla J.H. van der Kallen, J.H. Coes, Judith P. van Grafhorst, Ed M.D. Schuuring, Ferry A. Ossendorp, Joseph Helenus Hubert Thijssen, Marinus A. Blankenstein, Tjerk W.A. de Bruin;
Dissociation of thyrotropin receptor function and thyrotropin dependency in rat thyroid tumour cell lines derived from FRTL-5.
Br. J. Cancer 74:606-612(1996)

Cross-references
Encyclopedic resources Wikidata; Q107115080
Entry history
Entry creation20-May-2021
Last entry update10-Apr-2025
Version number7