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Cellosaurus UCONN-L2 (CVCL_A693)

[Text version]
Cell line name UCONN-L2
Synonyms UCONN-2
Accession CVCL_A693
Resource Identification Initiative To cite this cell line use: UCONN-L2 (RRID:CVCL_A693)
Sequence variations
Disease Anaplastic large cell lymphoma, ALK-positive (NCIt: C37193)
ALK-positive anaplastic large cell lymphoma (ORDO: Orphanet_300895)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=7824924; DOI=10.1126/science.8122112
Morris S.W., Kirstein M.N., Valentine M.B., Dittmer K.G., Shapiro D.N., Look A.T., Saltman D.L.
Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma.
Science 267:316-317(1995)

PubMed=8558920
Dirks W.G., Zaborski M., Jager K., Challier C., Shiota M., Quentmeier H., Drexler H.G.
The (2;5)(p23;q35) translocation in cell lines derived from malignant lymphomas: absence of t(2;5) in Hodgkin-analogous cell lines.
Leukemia 10:142-149(1996)

PubMed=9121481; DOI=10.1128/mcb.17.4.2312
Bischof D., Pulford K., Mason D.Y., Morris S.W.
Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis.
Mol. Cell. Biol. 17:2312-2325(1997)

PubMed=15356658; DOI=10.1038/sj.leu.2403465
Drexler H.G., MacLeod R.A.F.
Malignant hematopoietic cell lines: in vitro models for the study of anaplastic large-cell lymphoma.
Leukemia 18:1569-1571(2004)

Cross-references
Encyclopedic resources Wikidata; Q54989684
Polymorphism and mutation databases Cosmic; 1086005
Cosmic; 1086368
Cosmic; 1152616
Entry history
Entry creation06-Jun-2012
Last entry update21-Mar-2023
Version number15