ID   UCONN-L2
AC   CVCL_A693
SY   UCONN-2
DR   Cosmic; 1086005
DR   Cosmic; 1086368
DR   Cosmic; 1152616
DR   Wikidata; Q54989684
RX   PubMed=7824924;
RX   PubMed=8558920;
RX   PubMed=9121481;
RX   PubMed=15356658;
CC   Sequence variation: Gene fusion; HGNC; 427; ALK + HGNC; 7910; NPM1; Name(s)=NPM1-ALK (PubMed=7824924; PubMed=9121481).
DI   NCIt; C37193; Anaplastic large cell lymphoma, ALK-positive
DI   ORDO; Orphanet_300895; ALK-positive anaplastic large cell lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 21-03-23; Version: 15
//
RX   PubMed=7824924; DOI=10.1126/science.8122112;
RA   Morris S.W., Kirstein M.N., Valentine M.B., Dittmer K.G., Shapiro D.N.,
RA   Look A.T., Saltman D.L.;
RT   "Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in
RT   non-Hodgkin's lymphoma.";
RL   Science 267:316-317(1995).
//
RX   PubMed=8558920;
RA   Dirks W.G., Zaborski M., Jager K., Challier C., Shiota M.,
RA   Quentmeier H., Drexler H.G.;
RT   "The (2;5)(p23;q35) translocation in cell lines derived from malignant
RT   lymphomas: absence of t(2;5) in Hodgkin-analogous cell lines.";
RL   Leukemia 10:142-149(1996).
//
RX   PubMed=9121481; DOI=10.1128/mcb.17.4.2312;
RA   Bischof D., Pulford K., Mason D.Y., Morris S.W.;
RT   "Role of the nucleophosmin (NPM) portion of the non-Hodgkin's
RT   lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in
RT   oncogenesis.";
RL   Mol. Cell. Biol. 17:2312-2325(1997).
//
RX   PubMed=15356658; DOI=10.1038/sj.leu.2403465;
RA   Drexler H.G., MacLeod R.A.F.;
RT   "Malignant hematopoietic cell lines: in vitro models for the study of
RT   anaplastic large-cell lymphoma.";
RL   Leukemia 18:1569-1571(2004).
//