Cellosaurus cell line RLT-PSC (CVCL

Cellosaurus RLT-PSC (CVCL_A5TG)

Cross-references
Cell line name	RLT-PSC
Synonyms	i-hPSC
Accession	CVCL_A5TG
Resource Identification Initiative	To cite this cell line use: RLT-PSC (RRID:CVCL_A5TG)
Comments	Doubling time: 28.6 +- 2.5 hours (PubMed=30621293). Genetic integration: Method=Transfection; Gene=HGNC; HGNC:11730; TERT. Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Pancreas; UBERON=UBERON_0001264. Cell type: Pancreatic stellate cell; CL=CL_0002410.
Disease	Chronic pancreatitis (NCIt: C84637)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Adult
Category	Transformed cell line
Publications	PubMed=16127427; DOI=10.1038/labinvest.3700329 Ralf Jesenofsky, Daniel Furst, Jorg Ringel, Ying Chen, Andrea Schrodel, Jorg Kleeff, Armin Kolb, Wolfgang D. Schareck, Johannes-Matthias Lohr; Immortalization of pancreatic stellate cells as an in vitro model of pancreatic fibrosis: deactivation is induced by matrigel and N-acetylcysteine. Lab. Invest. 85:1276-1291(2005) PubMed=30621293; DOI=10.3390/cells8010023; PMCID=PMC6356867 Daniela Lenggenhager, Manoj Amrutkar, Petra Santha, Monica Aasrum, Johannes-Matthias Lohr, Ivar Prydz Gladhaug, Caroline Sophie Verbeke; Commonly used pancreatic stellate cell cultures differ phenotypically and in their interactions with pancreatic cancer cells. Cells 8:23.1-23.18(2019)
Encyclopedic resources	Wikidata; Q107116745
Entry history
Entry creation	20-May-2021
Last entry update	14-Aug-2025
Version number	8