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Cellosaurus RLT-PSC (CVCL_A5TG)

[Text version]
Cell line name RLT-PSC
Synonyms i-hPSC
Accession CVCL_A5TG
Resource Identification Initiative To cite this cell line use: RLT-PSC (RRID:CVCL_A5TG)
Comments Doubling time: 28.6 +- 2.5 hours (PubMed=30621293).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Cell type: Pancreatic stellate cell; CL=CL_0002410.
Disease Chronic pancreatitis (NCIt: C84637)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=16127427; DOI=10.1038/labinvest.3700329
Jesenofsky R., Furst D., Ringel J., Chen Y., Schrodel A., Kleeff J., Kolb A., Schareck W.D., Lohr J.-M.
Immortalization of pancreatic stellate cells as an in vitro model of pancreatic fibrosis: deactivation is induced by matrigel and N-acetylcysteine.
Lab. Invest. 85:1276-1291(2005)

PubMed=30621293; DOI=10.3390/cells8010023; PMCID=PMC6356867
Lenggenhager D., Amrutkar M., Santha P., Aasrum M., Lohr J.-M., Gladhaug I.P., Verbeke C.S.
Commonly used pancreatic stellate cell cultures differ phenotypically and in their interactions with pancreatic cancer cells.
Cells 8:23.1-23.18(2019)

Cross-references
Encyclopedic resources Wikidata; Q107116745
Entry history
Entry creation20-May-2021
Last entry update19-Dec-2024
Version number7