ID   RLT-PSC
AC   CVCL_A5TG
SY   i-hPSC
DR   Wikidata; Q107116745
RX   PubMed=16127427;
RX   PubMed=30621293;
CC   Doubling time: 28.6 +- 2.5 hours (PubMed=30621293).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
CC   Cell type: Pancreatic stellate cell; CL=CL_0002410.
DI   NCIt; C84637; Chronic pancreatitis
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Adult
CA   Transformed cell line
DT   Created: 20-05-21; Last updated: 19-12-24; Version: 7
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RX   PubMed=16127427; DOI=10.1038/labinvest.3700329;
RA   Jesenofsky R., Furst D., Ringel J., Chen Y., Schrodel A., Kleeff J.,
RA   Kolb A., Schareck W.D., Lohr J.-M.;
RT   "Immortalization of pancreatic stellate cells as an in vitro model of
RT   pancreatic fibrosis: deactivation is induced by matrigel and
RT   N-acetylcysteine.";
RL   Lab. Invest. 85:1276-1291(2005).
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RX   PubMed=30621293; DOI=10.3390/cells8010023; PMCID=PMC6356867;
RA   Lenggenhager D., Amrutkar M., Santha P., Aasrum M., Lohr J.-M.,
RA   Gladhaug I.P., Verbeke C.S.;
RT   "Commonly used pancreatic stellate cell cultures differ phenotypically
RT   and in their interactions with pancreatic cancer cells.";
RL   Cells 8:23.1-23.18(2019).
//