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Cellosaurus HSC-Li (CVCL_A5TB)

[Text version]
Cell line name HSC-Li
Accession CVCL_A5TB
Resource Identification Initiative To cite this cell line use: HSC-Li (RRID:CVCL_A5TB)
Comments Population: Chinese.
Characteristics: Produces both HGF and TGFB1 in a time-dependent manner (PubMed=25678842).
Doubling time: 8 hours (PubMed=25678842).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Hepatic stellate cell; CL=CL_0000632.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=25678842; DOI=10.7150/ijms.11002; PMCID=PMC4323363
Pan X.-P., Wang Y.-N., Yu X.-P., Li J.-Z., Zhou N., Du W.-B., Zhang Y.-H., Cao H.-C., Zhu D.-H., Chen Y., Li L.-J.
Establishment and characterization of an immortalized human hepatic stellate cell line for applications in co-culturing with immortalized human hepatocytes.
Int. J. Med. Sci. 12:248-255(2015)

PubMed=27020634; DOI=10.1016/S1499-3872(16)60074-7
Pan X.-P., Wang Y.-N., Yu X.-P., Zhu C.-X., Li J.-Z., Du W.-B., Zhang Y.-M., Cao H.-C., Zhang Y.-H., Zhu D.-H., Yeoh G.C.T., Li L.-J.
Efficient generation of functional hepatocyte-like cells from mouse liver progenitor cells via indirect co-culture with immortalized human hepatic stellate cells.
Hepatobiliary Pancreat. Dis. Int. 15:173-179(2016)

Cross-references
Encyclopedic resources Wikidata; Q107115364
Entry history
Entry creation20-May-2021
Last entry update19-Dec-2024
Version number7