ID   HSC-Li
AC   CVCL_A5TB
DR   Wikidata; Q107115364
RX   PubMed=25678842;
RX   PubMed=27020634;
CC   Population: Chinese.
CC   Characteristics: Produces both HGF and TGFB1 in a time-dependent manner (PubMed=25678842).
CC   Doubling time: 8 hours (PubMed=25678842).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Cell type: Hepatic stellate cell; CL=CL_0000632.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Adult
CA   Transformed cell line
DT   Created: 20-05-21; Last updated: 19-12-24; Version: 7
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RX   PubMed=25678842; DOI=10.7150/ijms.11002; PMCID=PMC4323363;
RA   Pan X.-P., Wang Y.-N., Yu X.-P., Li J.-Z., Zhou N., Du W.-B.,
RA   Zhang Y.-H., Cao H.-C., Zhu D.-H., Chen Y., Li L.-J.;
RT   "Establishment and characterization of an immortalized human hepatic
RT   stellate cell line for applications in co-culturing with immortalized
RT   human hepatocytes.";
RL   Int. J. Med. Sci. 12:248-255(2015).
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RX   PubMed=27020634; DOI=10.1016/S1499-3872(16)60074-7;
RA   Pan X.-P., Wang Y.-N., Yu X.-P., Zhu C.-X., Li J.-Z., Du W.-B.,
RA   Zhang Y.-M., Cao H.-C., Zhang Y.-H., Zhu D.-H., Yeoh G.C.T., Li L.-J.;
RT   "Efficient generation of functional hepatocyte-like cells from mouse
RT   liver progenitor cells via indirect co-culture with immortalized human
RT   hepatic stellate cells.";
RL   Hepatobiliary Pancreat. Dis. Int. 15:173-179(2016).
//