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Cellosaurus imWilms1 (CVCL_A5SN)

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Cell line name imWilms1
Synonyms IM-WT-1
Accession CVCL_A5SN
Resource Identification Initiative To cite this cell line use: imWilms1 (RRID:CVCL_A5SN)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations
Disease Kidney Wilms tumor (NCIt: C40407)
Nephroblastoma (ORDO: Orphanet_654)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A5SC (Wilms1-2l)
Sex of cell Female
Age at sampling 2Y
Category Conditionally immortalized cell line
STR profile Source(s): PubMed=33379206

Markers:
AmelogeninX
CSF1PO10
D3S135814,17
D5S81812,13
D7S8209,14
D8S117912,14
D13S31711,13
D16S53911,14
D18S5115,18
D21S1130,31
FGA22,25
Penta D13
Penta E5,14
TH019.3
TPOX8,9
vWA14,19

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Publications

PubMed=33379206; DOI=10.3390/cancers13010060; PMCID=PMC7801943
Brigitte Royer-Pokora, Maike Anna Busch, Sarah Tenbusch, Mathias Schmidt, Manfred Beier, Andrew D. Woods, Holger Thiele, Jaume Mora;
Comprehensive biology and genetics compendium of Wilms tumor cell lines with different WT1 mutations.
Cancers (Basel) 13:60.1-60.21(2021)

Cross-references
Cell line collections (Providers) CLS; 300412
Encyclopedic resources Wikidata; Q107115459
Entry history
Entry creation20-May-2021
Last entry update14-Aug-2025
Version number10