Cellosaurus cell line Wilms6 (CVCL

Cellosaurus Wilms6 (CVCL_A5SI)

[Text version]

Cell line name

Wilms6

Accession

CVCL_A5SI

Resource Identification Initiative

To cite this cell line use: Wilms6 (RRID:CVCL_A5SI)

Comments

Population: Caucasian.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.

Sequence variations

Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ser45del (c.133_135delTCT); ClinVar=VCV000017576; Zygosity=Homozygous (PubMed=33379206).
Mutation; HGNC; HGNC:12796; WT1; Simple; p.Arg390Ter (c.1168C>T) (p.Arg463Ter, c.1387C>T); ClinVar=VCV000003494; Zygosity=Homozygous (PubMed=33379206).

Disease

Kidney Wilms tumor (NCIt: C40407)
Nephroblastoma (ORDO: Orphanet_654)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Children:

CVCL_A5SQ (imWilms6)

Sex of cell

Male

Age at sampling

1Y3M

Category

Finite cell line

STR profile

Source(s): CLS=300415; PubMed=33379206

Markers:

Amelogenin	X,Y
CSF1PO	11,12
D3S1358	15,16
D5S818	8,9
D7S820	8,11
D8S1179	11,13
D13S317	8,11
D16S539	9,11
D18S51	12,16
D21S11	28,30
FGA	22,23
Penta D	11
Penta E	8,13
TH01	9
TPOX	11
vWA	16,18

Publications

PubMed=33379206; DOI=10.3390/cancers13010060; PMCID=PMC7801943
Brigitte Royer-Pokora, Maike Anna Busch, Sarah Tenbusch, Mathias Schmidt, Manfred Beier, Andrew D. Woods, Holger Thiele, Jaume Mora;
Comprehensive biology and genetics compendium of Wilms tumor cell lines with different WT1 mutations.
Cancers (Basel) 13:60.1-60.21(2021)

Cross-references

Cell line collections (Providers)

CLS; 300415

Encyclopedic resources

Wikidata; Q107117473

Entry history

Entry creation

20-May-2021

Last entry update

19-Dec-2024

Version number