Cellosaurus cell line CD#68 iPSC (CVCL

Cellosaurus CD#68 iPSC (CVCL_A5RM)

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Cell line name

CD#68 iPSC

Accession

CVCL_A5RM

Resource Identification Initiative

To cite this cell line use: CD#68 iPSC (RRID:CVCL_A5RM)

Comments

Population: Jewish.
Cell type: Fibroblast; CL=CL_0000057.

Sequence variations

Mutation; HGNC; HGNC:756; ASPA; Simple; p.Glu285Ala (c.854A>C); ClinVar=VCV000002605; Zygosity=Homozygous (PubMed=33304759).

Disease

Canavan disease (NCIt: C84611)
Canavan disease (ORDO: Orphanet_141)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_0P45 (GM04268)
Children:

CVCL_A5RU (CD#68T-13 iPSC)

Sex of cell

Male

Age at sampling

Category

Induced pluripotent stem cell

STR profile

Source(s): PubMed=33304759

Markers:

Amelogenin	X,Y
CSF1PO	11
D5S818	10,12
D7S820	9,12
D13S317	11,12
D16S539	10,13
D21S11	29,31.2
TH01	9,9.3
TPOX	9,11
vWA	17,18

Publications

PubMed=33304759; DOI=10.1002/advs.202002155; PMCID=PMC7709977
Li-Zhao Feng, Jian-Fei Chao, E. Tian, Li Li, Peng Ye, Mi Zhang, Xian-Wei Chen, Qi Cui, Gui-Hua Sun, Tao Zhou, Gerardo Felix ...Show all 24 authors... , Yue Qin, Wen-Dong Li, Edward David Meza, Jeremy Klein, Lucy Y. Ghoda, Wei-Dong Hu, Yong-Lun Luo, Wei Dang, David Hsu, Joseph D. Gold, Steven A. Goldman, Reuben Karl Matalon, Yan-Hong Shi; Show fewer authors
Cell-based therapy for Canavan disease using human iPSC-derived NPCs and OPCs.
Adv. Sci. (Weinh.) 7:2002155.1-2002155.19(2020)

Cross-references

Encyclopedic resources

Wikidata; Q107114634

Entry history

Entry creation

20-May-2021

Last entry update

19-Dec-2024

Version number