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Cellosaurus A549-hACE2 [Invivogen] (CVCL_A5KA)

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Cell line name A549-hACE2 [Invivogen]
Accession CVCL_A5KA
Resource Identification Initiative To cite this cell line use: A549-hACE2 [Invivogen] (RRID:CVCL_A5KA)
Comments Group: SARS-CoV-2 research cell line.
Population: Caucasian.
Characteristics: Permissive to infection by SARS-CoV-2 and/or spike-pseudotyped lentiviral particles (InvivoGen=a549-hace2).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:13557; ACE2.
Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Children:
CVCL_A5KB (A549-hACE2-TMPRSS2)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) InvivoGen; a549-hace2
Cell line databases/resources cancercelllines; CVCL_A5KA
Encyclopedic resources Wikidata; Q107113335
Entry history
Entry creation20-May-2021
Last entry update14-Aug-2025
Version number9