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Cellosaurus AF22 (CVCL_A5CW)

[Text version]
Cell line name AF22
Accession CVCL_A5CW
Resource Identification Initiative To cite this cell line use: AF22 (RRID:CVCL_A5CW)
Comments Part of: Human Protein Atlas, Cell Atlas panel.
Characteristics: Long term self-renewing neuroepithelial-like stem cells with stable neurogenic properties (PubMed=22272239).
Omics: Proteomics; Expression; Large antibody panel staining analysis.
Omics: Transcriptomics; RNAseq.
Miscellaneous: Sex of donor from personal communication of BioKryo (ISENET Biobanking).
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 36Y
Category Somatic stem cell
Web pages Info; HPA; -; https://www.proteinatlas.org/learn/cellines
Provider; BioKryo; -; https://biokryo.airliquide.com/sites/biokryo/files/2022-07/human-stem-cells-catalogue-isenet.pdf
Publications

PubMed=22272239; DOI=10.1371/journal.pone.0029597; PMCID=PMC3260177
Falk A., Koch P., Kesavan J., Takashima Y., Ladewig J., Alexander M., Wiskow O., Tailor J., Trotter M., Pollard S.M., Smith A.G., Brustle O.
Capture of neuroepithelial-like stem cells from pluripotent stem cells provides a versatile system for in vitro production of human neurons.
PLoS ONE 7:e29597.1-e29597.13(2012)

PubMed=23884946; DOI=10.1523/JNEUROSCI.0130-13.2013; PMCID=PMC3721847
Tailor J., Kittappa R., Leto K., Gates M., Borel M., Paulsen O., Spitzer S., Karadottir R.T., Rossi F., Falk A., Smith A.G.
Stem cells expanded from the human embryonic hindbrain stably retain regional specification and high neurogenic potency.
J. Neurosci. 33:12407-12422(2013)

PubMed=28041877; DOI=10.1016/j.stemcr.2016.11.014; PMCID=PMC5233436
Flores J.V., Cordero-Espinoza L., Oeztuerk-Winder F., Andersson-Rolf A., Selmi T., Blanco S., Tailor J., Dietmann S., Frye M.
Cytosine-5 RNA methylation regulates neural stem cell differentiation and motility.
Stem Cell Reports 8:112-124(2017)

Cross-references
Anatomy/cell type resources BTO; BTO_0006445
Encyclopedic resources Wikidata; Q107113349
Gene expression databases GEO; GSM7701478
GEO; GSM7701479
Entry history
Entry creation20-May-2021
Last entry update10-Apr-2025
Version number8