ID   AF22
AC   CVCL_A5CW
DR   BTO; BTO_0006445
DR   GEO; GSM7701478
DR   GEO; GSM7701479
DR   Wikidata; Q107113349
RX   PubMed=22272239;
RX   PubMed=23884946;
RX   PubMed=28041877;
WW   Info; HPA; -; https://www.proteinatlas.org/learn/cellines
WW   Provider; BioKryo; -; https://biokryo.airliquide.com/sites/biokryo/files/2022-07/human-stem-cells-catalogue-isenet.pdf
CC   Part of: Human Protein Atlas, Cell Atlas panel.
CC   Characteristics: Long term self-renewing neuroepithelial-like stem cells with stable neurogenic properties (PubMed=22272239).
CC   Omics: Proteomics; Expression; Large antibody panel staining analysis.
CC   Omics: Transcriptomics; RNAseq.
CC   Miscellaneous: Sex of donor from personal communication of BioKryo (ISENET Biobanking).
CC   Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   36Y
CA   Somatic stem cell
DT   Created: 20-05-21; Last updated: 10-04-25; Version: 8
//
RX   PubMed=22272239; DOI=10.1371/journal.pone.0029597; PMCID=PMC3260177;
RA   Falk A., Koch P., Kesavan J., Takashima Y., Ladewig J., Alexander M.,
RA   Wiskow O., Tailor J., Trotter M., Pollard S.M., Smith A.G., Brustle O.;
RT   "Capture of neuroepithelial-like stem cells from pluripotent stem
RT   cells provides a versatile system for in vitro production of human
RT   neurons.";
RL   PLoS ONE 7:e29597.1-e29597.13(2012).
//
RX   PubMed=23884946; DOI=10.1523/JNEUROSCI.0130-13.2013; PMCID=PMC3721847;
RA   Tailor J., Kittappa R., Leto K., Gates M., Borel M., Paulsen O.,
RA   Spitzer S., Karadottir R.T., Rossi F., Falk A., Smith A.G.;
RT   "Stem cells expanded from the human embryonic hindbrain stably retain
RT   regional specification and high neurogenic potency.";
RL   J. Neurosci. 33:12407-12422(2013).
//
RX   PubMed=28041877; DOI=10.1016/j.stemcr.2016.11.014; PMCID=PMC5233436;
RA   Flores J.V., Cordero-Espinoza L., Oeztuerk-Winder F.,
RA   Andersson-Rolf A., Selmi T., Blanco S., Tailor J., Dietmann S.,
RA   Frye M.;
RT   "Cytosine-5 RNA methylation regulates neural stem cell differentiation
RT   and motility.";
RL   Stem Cell Reports 8:112-124(2017).
//