• Gene fusion; HGNC; HGNC:23139; CLVS1 + HGNC; HGNC:9709; PVT1; Name(s)=PVT1-CLVS1 (from parent cell line).
  
• Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Gln546Lys (c.1636C>A); ClinVar=VCV000013657; Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu298Ter (c.892G>T); ClinVar=VCV000093323; Zygosity=Unspecified (from parent cell line).
  

PubMed=6108156
Adi F. Gazdar, Desmond Niall Carney, Edward K. Russell, Harvie L. Sims, Stephen Bruce Baylin, Paul A. Bunn Jr., John G. Guccion, John D. Minna;
Establishment of continuous, clonable cultures of small-cell carcinoma of lung which have amine precursor uptake and decarboxylation cell properties.
Cancer Res. 40:3502-3507(1980)

PubMed=6270685; DOI=10.1073/pnas.78.7.4591; PMCID=PMC319839
Frank Cuttitta, Steven T. Rosen, Adi F. Gazdar, John D. Minna;
Monoclonal antibodies that demonstrate specificity for several types of human lung cancer.
Proc. Natl. Acad. Sci. U.S.A. 78:4591-4595(1981)

PubMed=6272398; DOI=10.1126/science.6272398
Terry W. Moody, Candace Beebe Pert, Adi F. Gazdar, Desmond Niall Carney, John D. Minna;
High levels of intracellular bombesin characterize human small-cell lung carcinoma.
Science 214:1246-1248(1981)

PubMed=6713399
Steven T. Rosen, James L. Mulshine, Frank Cuttitta, Joseph Fedorko, Desmond Niall Carney, Adi F. Gazdar, John D. Minna;
Analysis of human small cell lung cancer differentiation antigens using a panel of rat monoclonal antibodies.
Cancer Res. 44:2052-2061(1984)

PubMed=2985257
Desmond Niall Carney, Adi F. Gazdar, Gerold Bepler, John G. Guccion, Paul J. Marangos, Terry W. Moody, Mark H. Zweig, John D. Minna;
Establishment and identification of small cell lung cancer cell lines having classic and variant features.
Cancer Res. 45:2913-2923(1985)

PubMed=2985258
Adi F. Gazdar, Desmond Niall Carney, Marion M. Nau, John D. Minna;
Characterization of variant subclasses of cell lines derived from small cell lung cancer having distinctive biochemical, morphological, and growth properties.
Cancer Res. 45:2924-2930(1985)

PubMed=2986243; DOI=10.1007/978-3-642-82372-5_4
Jacqueline Whang-Peng, Elaine C. Lee;
Cytogenetics of human small cell lung cancer.
Recent Results Cancer Res. 97:37-46(1985)

PubMed=1563005
Giuseppe Giaccone, James Battey, Adi F. Gazdar, Herbert Kazuto Oie, Muriel Draoui, Terry W. Moody;
Neuromedin B is present in lung cancer cell lines.
Cancer Res. 52:2732s-2736s(1992)

PubMed=8626706; DOI=10.1074/jbc.271.19.11477
Kathryn A. Quinn, Anthony M. Treston, Edward J. Unsworth, Mae-Jean Miller, Michele Vos, Chris Grimley, James Battey, James L. Mulshine, Frank Cuttitta;
Insulin-like growth factor expression in human cancer cell lines.
J. Biol. Chem. 271:11477-11483(1996)

PubMed=8806092; DOI=10.1002/jcb.240630505
Ruby M. Phelps, Bruce E. Johnson, Daniel C. Ihde, Adi F. Gazdar, David P. Carbone, Patrick R. McClintock, Ritva Ilona Linnoila, Mary J. Matthews, Paul A. Bunn Jr., Desmond Niall Carney, John D. Minna, James L. Mulshine;
NCI-Navy Medical Oncology Branch cell line data base.
J. Cell. Biochem. Suppl. 24:32-91(1996)

PubMed=8806103; DOI=10.1002/jcb.240630516
Bruce E. Johnson, Edward Russell, Alfreda M. Simmons, Ruby M. Phelps, Seth M. Steinberg, Daniel C. Ihde, Adi F. Gazdar;
MYC family DNA amplification in 126 tumor cell lines from patients with small cell lung cancer.
J. Cell. Biochem. Suppl. 24:210-217(1996)

PubMed=11030152; DOI=10.1038/sj.onc.1203815
Sanjay Modi, Akihito Kubo, Herbert Kazuto Oie, Amy B. Coxon, Ahad Rehmatulla, Frederic J. Kaye;
Protein expression of the RB-related gene family and SV40 large T antigen in mesothelioma and lung cancer.
Oncogene 19:4632-4639(2000)

PubMed=31803961; DOI=10.1002/jcb.29564; PMCID=PMC7496084
James L. Mulshine, Peter Ujhazy, Melissa Antman, Christine M. Burgess, Igor A. Kuzmin, Paul A. Bunn Jr., Bruce E. Johnson, Jack Alan Roth, Harvey I. Pass, Sheila M. Ross, Carolyn R. Aldige ...Show all 13 authors... , Ignacio Ivan Wistuba, John D. Minna; Show fewer authors
From clinical specimens to human cancer preclinical models -- a journey the NCI-cell line database-25 years later.
J. Cell. Biochem. 121:3986-3999(2020)