Cellosaurus cell line MiPSC5 (CVCL

Cellosaurus MiPSC5 (CVCL_A4RE)

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Cell line name

MiPSC5

Accession

CVCL_A4RE

Resource Identification Initiative

To cite this cell line use: MiPSC5 (RRID:CVCL_A4RE)

Comments

Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.

Sequence variations

Mutation; HGNC; HGNC:7490; MT-TL1; Simple; m.3243A>G; ClinVar=VCV000009589; Zygosity=Heteroplasmic; Note=In >80% of cells (PubMed=29318513).

Disease

MELAS syndrome (NCIt: C84885)
MELAS (ORDO: Orphanet_550)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Children:

CVCL_A4RF (MiPSC5-T1)

CVCL_A4RG (MiPSC5-T3)

CVCL_A4RH (MiPSC5-T7)

Sex of cell

Male

Age at sampling

Age unspecified

Category

Induced pluripotent stem cell

Publications

PubMed=29318513; DOI=10.1007/s13238-017-0499-y; PMCID=PMC5829275
Yi Yang, Han Wu, Xiang-Jin Kang, Yan-Hui Liang, Ting Lan, Tian-Jie Li, Tao Tan, Jiang-Yun Peng, Quan-Jun Zhang, Geng An, Ya-Li Liu ...Show all 25 authors... , Qian Yu, Zheng-Lai Ma, Ying Lian, Boon Seng Soh, Qing-Feng Chen, Ping Liu, Yao-Yong Chen, Xiao-Fang Sun, Rong Li, Xiu-Mei Zhen, Ping Liu, Yang Yu, Xiao-Ping Li, Yong Fan; Show fewer authors
Targeted elimination of mutant mitochondrial DNA in MELAS-iPSCs by mitoTALENs.
Protein Cell 9:283-297(2018)

Cross-references

Cell line databases/resources

SKIP; SKIP002968

Encyclopedic resources

Wikidata; Q105510144

Entry history

Entry creation

12-Jan-2021

Last entry update

19-Dec-2024

Version number