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Cellosaurus Trpl43 (CVCL_A4QW)

[Text version]
Cell line name Trpl43
Accession CVCL_A4QW
Resource Identification Initiative To cite this cell line use: Trpl43 (RRID:CVCL_A4QW)
Comments Population: Caucasian.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Gene amplification; HGNC; HGNC:11138; SNCA; Triplication; Zygosity=Unspecified (PubMed=22110584).
Disease Parkinson disease 4, autosomal dominant (NCIt: C198604)
Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A4QU ! Trpl8
CVCL_A4QV ! Trpl17
Sex of cell Male
Age at sampling 48Y
Category Induced pluripotent stem cell
Publications

PubMed=22110584; DOI=10.1371/journal.pone.0026159; PMCID=PMC3217921
Byers B., Cord B., Nguyen H.N., Schule B., Fenno L., Lee P.C., Deisseroth K.A., Langston J.W., Reijo Pera R.A., Palmer T.D.
SNCA triplication Parkinson's patient's iPSC-derived DA neurons accumulate alpha-synuclein and are susceptible to oxidative stress.
PLoS ONE 6:e26159.1-e26159.13(2011)

Cross-references
Encyclopedic resources Wikidata; Q105511269
Entry history
Entry creation12-Jan-2021
Last entry update19-Dec-2024
Version number7