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Cellosaurus LNCaP clone FGC-Luc2 (CVCL_A4BQ)

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Cell line name LNCaP clone FGC-Luc2
Accession CVCL_A4BQ
Resource Identification Initiative To cite this cell line use: LNCaP clone FGC-Luc2 (RRID:CVCL_A4BQ)
Comments Population: Caucasian.
Characteristics: Stably expresses firefly luciferase under the control of the human EF1a promoter (ATCC=CRL-1740-LUC2).
Doubling time: 40.8 hours (ATCC=CRL-1740-LUC2).
Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; Bacillus cereus Bsr.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase (Note=With optimized codon usage for mammalian expression = Luc2).
Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056.
Sequence variations
  • Mutation; HGNC; HGNC:644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; HGNC:7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1379 (LNCaP clone FGC)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-1740-LUC2

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S81811,12
D7S8209.1,10.3
D13S31710,12
D16S53911
TH019
TPOX8,9
vWA16,18

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Cross-references
Cell line collections (Providers) ATCC; CRL-1740-LUC2
Cell line databases/resources cancercelllines; CVCL_A4BQ
Encyclopedic resources Wikidata; Q105509918
Entry history
Entry creation12-Jan-2021
Last entry update14-Aug-2025
Version number11