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Cellosaurus M6C (CVCL_A4AV)

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Cell line name M6C
Accession CVCL_A4AV
Resource Identification Initiative To cite this cell line use: M6C (RRID:CVCL_A4AV)
Comments Characteristics: Metastatic. Established from a nude mice lung metastasis obtained by subcutaneous injection of the parent cell line (PubMed=12602905).
Doubling time: 15 hours (PubMed=12602905).
Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen (Note=Under the control of the promoter of rat Psbpc3/Scgb2a2).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Disease Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: FVB-Tg(C3-1-TAg)cJeg/JegJ transgenic.
Hierarchy Parent: CVCL_A4AU (M6)
Sex of cell Female
Age at sampling 5-6M
Category Cancer cell line
Publications

PubMed=12602905; DOI=10.1023/A:1021175931177
Ryan G. Holzer, Christina MacDougall, Gerry Cortright, Kristi Atwood, Jeffrey E. Green, Cheryl Lynn Jorcyk;
Development and characterization of a progressive series of mammary adenocarcinoma cell lines derived from the C3(1)/SV40 Large T-antigen transgenic mouse model.
Breast Cancer Res. Treat. 77:65-76(2003)

Cross-references
Encyclopedic resources Wikidata; Q105510001
Entry history
Entry creation12-Jan-2021
Last entry update27-Nov-2025
Version number7