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Cellosaurus SW850 (CVCL_A424)

[Text version]
Cell line name SW850
Synonyms SW-850; SW 850
Accession CVCL_A424
Resource Identification Initiative To cite this cell line use: SW850 (RRID:CVCL_A424)
Comments Problematic cell line: Possibly misidentified/contaminated. Reported by PubMed=11787853 to contain the same HPV18 sequences as the cervix carcinoma cell line C-4-I (Cellosaurus=CVCL_2253) and to lack mutations in KRAS, TP53, CDKN2A and DPC4 often found in pancreatic adenocarcinoma. Considered by PubMed=25997541 to be a bladder carcinoma cell line.
Part of: UBC-40 urothelial bladder cancer cell line index.
From: Scott and White Clinic; Temple; USA.
Omics: Variations; SNP array analysis.
Disease Pancreatic adenocarcinoma (NCIt: C8294)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=327080; DOI=10.1093/jnci/59.1.221
Jorgen Fogh, Jens M. Fogh, Thomas Orfeo;
One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice.
J. Natl. Cancer Inst. 59:221-226(1977)

PubMed=833871; DOI=10.1093/jnci/58.2.209
Jorgen Fogh, William C. Wright, James D. Loveless;
Absence of HeLa cell contamination in 169 cell lines derived from human tumors.
J. Natl. Cancer Inst. 58:209-214(1977)

PubMed=6220172
Nicholas C. Dracopoli, Jorgen Fogh;
Polymorphic enzyme analysis of cultured human tumor cell lines.
J. Natl. Cancer Inst. 70:469-476(1983)

PubMed=1906154
Holger Kalthoff, Christian Roeder, Inge Humburg, Heinz-Gunter Thiele, Heiner Greten, Wolff Helmut Schmiegel;
Modulation of platelet-derived growth factor A- and B-chain/c-sis mRNA by tumor necrosis factor and other agents in adenocarcinoma cells.
Oncogene 6:1015-1021(1991)

PubMed=8426738
Holger Kalthoff, Wolff Helmut Schmiegel, Christian Roeder, Daniela Kasche, Andreas Schmidt, Georg Lauer, Heinz-Gunter Thiele, Georg Honold, Klaus Pantel, Gert Riethmuller, Ewalt Scherer ...Show all 14 authors... , Julian Maurer, Heiko Maacke, Wolfgang Deppert; Show fewer authors
p53 and K-RAS alterations in pancreatic epithelial cell lesions.
Oncogene 8:289-298(1993)

PubMed=9472115; DOI=10.3892/ijo.12.3.717
Carsten Muller, Andreas Clemens Grosse Bockhorn, Simone Klusmeier, Michael Kiehl, Christian Roeder, Holger Kalthoff, Olaf M. Koch;
Lovastatin inhibits proliferation of pancreatic cancer cell lines with mutant as well as with wild-type K-ras oncogene but has different effects on protein phosphorylation and induction of apoptosis.
Int. J. Oncol. 12:717-723(1998)

PubMed=11787853; DOI=10.1007/s004280100474
Patrick S. Moore, Bence Sipos, Simonetta Orlandini, Claudio Sorio, Francisco X. Real, Nicholas Robert Lemoine, Thomas M. Gress, Claudio Bassi, Gunter Kloppel, Holger Kalthoff, Hendrik Ungefroren ...Show all 13 authors... , Johannes-Matthias Lohr, Aldo Scarpa; Show fewer authors
Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4.
Virchows Arch. 439:798-802(2001)

PubMed=25997541; DOI=10.1186/s12864-015-1450-3; PMCID=PMC4470036
Julie Earl, Daniel Rico, Enrique Carrillo-de-Santa-Pau, Benjamin Rodriguez-Santiago, Marinela Mendez-Pertuz, Herbert Auer, Gonzalo Gomez, Herbert Barton Grossman, David G. Pisano, Wolfgang A. Schulz, Luis A. Perez-Jurado ...Show all 16 authors... , Alfredo Carrato, Dan Theodorescu, Stephen Jacob Chanock, Alfonso Valencia, Francisco X. Real; Show fewer authors
The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies.
BMC Genomics 16:403.1-403.16(2015)

PubMed=26621286; DOI=10.1186/s12864-015-2227-4; PMCID=PMC4681452
Julie Earl, Daniel Rico, Enrique Carrillo-de-Santa-Pau, Benjamin Rodriguez-Santiago, Marinela Mendez-Pertuz, Herbert Auer, Gonzalo Gomez, Herbert Barton Grossman, David G. Pisano, Wolfgang A. Schulz, Luis A. Perez-Jurado ...Show all 16 authors... , Alfredo Carrato, Dan Theodorescu, Stephen Jacob Chanock, Alfonso Valencia, Francisco X. Real; Show fewer authors
Erratum to: The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies.
BMC Genomics 16:1019.1-1019.2(2015)

Cross-references
Encyclopedic resources Wikidata; Q54971214
Gene expression databases GEO; GSM1567856
Polymorphism and mutation databases Cosmic; 736278
Cosmic; 933518
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number17