PubMed=18035408; DOI=10.1016/j.cell.2007.11.019
Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki, Megumi Narita, Tomoko Ichisaka, Kiichiro Tomoda, Shinya Yamanaka;
Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
Cell 131:861-872(2007)

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Kazutoshi Takahashi, Megumi Narita, Midori Yokura, Tomoko Ichisaka, Shinya Yamanaka;
Human induced pluripotent stem cells on autologous feeders.
PLoS ONE 4:e8067.1-e8067.6(2009)

PubMed=21098095; DOI=10.1084/jem.20100844; PMCID=PMC3005234
Naoya Takayama, Satoshi Nishimura, Sou Nakamura, Takafumi Shimizu, Ryoko Ohnishi, Hiroshi Endo, Tomoyuki Yamaguchi, Makoto Otsu, Ken Nishimura, Mahito Nakanishi, Akira Sawaguchi ...Show all 16 authors... , Ryozo Nagai, Kazutoshi Takahashi, Shinya Yamanaka, Hiromitsu Nakauchi, Koji Eto; Show fewer authors
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J. Exp. Med. 207:2817-2830(2010)

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Keisuke Okita, Yasuko Matsumura, Yoshiko Sato, Atsumasa Okada, Asuka Morizane, Satoshi Okamoto, Hyen-Jong Hong, Masato Nakagawa, Koji Tanabe, Ken-ichi Tezuka, Toshiyuki Shibata ...Show all 16 authors... , Takahiro Kunisada, Masayo Takahashi, Jun Takahashi, Hiroh Saji, Shinya Yamanaka; Show fewer authors
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Nat. Methods 8:409-412(2011)

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Koichiro Nishino, Masashi Toyoda, Mayu Yamazaki-Inoue, Yoshihiro Fukawatase, Emi Chikazawa, Hironari Sakaguchi, Hidenori Akutsu, Akihiro Umezawa;
DNA methylation dynamics in human induced pluripotent stem cells over time.
PLoS Genet. 7:e1002085.1-e1002085.14(2011)

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Takuya Yagi, Daisuke Ito, Yohei Okada, Wado Akamatsu, Yoshihiro Nihei, Takahito Yoshizaki, Shinya Yamanaka, Hideyuki Okano, Norihiro Suzuki;
Modeling familial Alzheimer's disease with induced pluripotent stem cells.
Hum. Mol. Genet. 20:4530-4539(2011)

PubMed=22056147; DOI=10.1016/j.scr.2011.10.002
Yuya Kunisada, Noriko Tsubooka-Yamazoe, Masanobu Shoji, Masaki Hosoya;
Small molecules induce efficient differentiation into insulin-producing cells from human induced pluripotent stem cells.
Stem Cell Res. 8:274-284(2012)

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Masatoshi Kajiwara, Takashi Aoi, Keisuke Okita, Ryosuke Takahashi, Haruhisa Inoue, Naoya Takayama, Hiroshi Endo, Koji Eto, Junya Toguchida, Shinji Uemoto, Shinya Yamanaka;
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells.
Proc. Natl. Acad. Sci. U.S.A. 109:12538-12543(2012)

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Takuya Yagi, Arifumi Kosakai, Daisuke Ito, Yohei Okada, Wado Akamatsu, Yoshihiro Nihei, Akira Nabetani, Fuyuki Ishikawa, Yasumichi Arai, Nobuyoshi Hirose, Hideyuki Okano, Norihiro Suzuki;
Establishment of induced pluripotent stem cells from centenarians for neurodegenerative disease research.
PLoS ONE 7:e41572.1-e41572.7(2012)

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Yoichi Imaizumi, Yohei Okada, Wado Akamatsu, Masato Koike, Naoko Kuzumaki, Hideki Hayakawa, Tomoko Nihira, Tetsuro Kobayashi, Manabu Ohyama, Shigeto Sato, Masashi Takanashi ...Show all 30 authors... , Manabu Funayama, Akiyoshi Hirayama, Tomoyoshi Soga, Takako Hishiki, Makoto Suematsu, Takuya Yagi, Daisuke Ito, Arifumi Kosakai, Kozo Hayashi, Masanobu Shouji, Atsushi Nakanishi, Norihiro Suzuki, Yoshikuni Mizuno, Noboru Mizushima, Masayuki Amagai, Yasuo Uchiyama, Hideki Mochizuki, Nobutaka Hattori, Hideyuki Okano; Show fewer authors
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Mol. Brain 5:35.1-35.13(2012)

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Ryota Yamana, Mio Iwasaki, Masaki Wakabayashi, Masato Nakagawa, Shinya Yamanaka, Yasushi Ishihama;
Rapid and deep profiling of human induced pluripotent stem cell proteome by one-shot NanoLC-MS/MS analysis with meter-scale monolithic silica columns.
J. Proteome Res. 12:214-221(2013)

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Michiyo Koyanagi-Aoi, Mari Ohnuki, Kazutoshi Takahashi, Keisuke Okita, Hisashi Noma, Yuka Sawamura, Ito Teramoto, Megumi Narita, Yoshiko Sato, Tomoko Ichisaka, Naoki Amano ...Show all 17 authors... , Akira Watanabe, Asuka Morizane, Yasuhiro Yamada, Tosiya Sato, Jun Takahashi, Shinya Yamanaka; Show fewer authors
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Proc. Natl. Acad. Sci. U.S.A. 110:20569-20574(2013)

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Masato Nakagawa, Yukimasa Taniguchi, Sho Senda, Nanako Takizawa, Tomoko Ichisaka, Kanako Asano, Asuka Morizane, Daisuke Doi, Jun Takahashi, Masatoshi Nishizawa, Yoshinori Yoshida ...Show all 15 authors... , Taro Toyoda, Kenji Osafune, Kiyotoshi Sekiguchi, Shinya Yamanaka; Show fewer authors
A novel efficient feeder-free culture system for the derivation of human induced pluripotent stem cells.
Sci. Rep. 4:3594.1-3594.7(2014)

PubMed=24935155; DOI=10.1186/1756-6606-7-45; PMCID=PMC4058693
Tetsu Yoshida, Yoko Ozawa, Keiichiro Suzuki, Kenya Yuki, Manabu Ohyama, Wado Akamatsu, Yumi Matsuzaki, Shigeto Shimmura, Kohnosuke Mitani, Kazuo Tsubota, Hideyuki Okano;
The use of induced pluripotent stem cells to reveal pathogenic gene mutations and explore treatments for retinitis pigmentosa.
Mol. Brain 7:45.1-45.11(2014)

PubMed=26626025; DOI=10.1186/s13041-015-0172-4; PMCID=PMC4666063
Daisuke Shimojo, Kazunari Onodera, Yukiko Doi-Torii, Yasuharu Ishihara, Chinatsu Hattori, Yukino Miwa, Satoshi Tanaka, Rina Okada, Manabu Ohyama, Masanobu Shoji, Atsushi Nakanishi ...Show all 14 authors... , Manabu Doyu, Hideyuki Okano, Yohei Okada; Show fewer authors
Rapid, efficient, and simple motor neuron differentiation from human pluripotent stem cells.
Mol. Brain 8:79.1-79.15(2015)

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Masatoshi Nishizawa, Kazuhisa Chonabayashi, Masaki Nomura, Azusa Tanaka, Masahiro Nakamura, Azusa Inagaki, Misato Nishikawa, Ikue Takei, Akiko Oishi, Koji Tanabe, Mari Ohnuki ...Show all 18 authors... , Hidaka Yokota, Michiyo Koyanagi-Aoi, Keisuke Okita, Akira Watanabe, Akifumi Takaori-Kondo, Shinya Yamanaka, Yoshinori Yoshida; Show fewer authors
Epigenetic variation between human induced pluripotent stem cell lines is an indicator of differentiation capacity.
Cell Stem Cell 19:341-354(2016)

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Yoshihito Ishida, Hideshi Kawakami, Hiroyuki Kitajima, Ayaka Nishiyama, Yoshiki Sasai, Haruhisa Inoue, Keiko Muguruma;
Vulnerability of Purkinje cells generated from spinocerebellar ataxia type 6 patient-derived iPSCs.
Cell Rep. 17:1482-1490(2016)

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Shihori Yokobayashi, Keisuke Okita, Masato Nakagawa, Tomonori Nakamura, Yukihiro Yabuta, Takuya Yamamoto, Mitinori Saitou;
Clonal variation of human induced pluripotent stem cells for induction into the germ cell fate.
Biol. Reprod. 96:1154-1166(2017)

PubMed=29179815; DOI=10.7554/eLife.21114; PMCID=PMC5705211
Hironobu Okuno, Francois Renault-Mihara, Shigeki Ohta, Kimiko Fukuda, Kenji Kurosawa, Wado Akamatsu, Tsukasa Sanosaka, Jun Kohyama, Kanehiro Hayashi, Kazunori Nakajima, Takao Takahashi ...Show all 14 authors... , Joanna K. Wysocka, Kenjiro Kosaki, Hideyuki Okano; Show fewer authors
CHARGE syndrome modeling using patient-iPSCs reveals defective migration of neural crest cells harboring CHD7 mutations.
eLife 6:e21114.1-e21114.26(2017)

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Sanami Takada, Naotomo Kambe, Yuri Kawasaki, Akira Niwa, Fumiko Honda-Ozaki, Kazuki Kobayashi, Mitsujiro Osawa, Ayako Nagahashi, Katsunori Semi, Akitsu Hotta, Isao Asaka ...Show all 17 authors... , Yasuhiro Yamada, Ryuta Nishikomori, Toshio Heike, Hiroyuki Matsue, Tatsutoshi Nakahata, Megumu K. Saito; Show fewer authors
Pluripotent stem cell models of Blau syndrome reveal an IFN-gamma-dependent inflammatory response in macrophages.
J. Allergy Clin. Immunol. 141:339-349.e11(2018)

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Koki Fujimori, Mitsuru Ishikawa, Asako Otomo, Naoki Atsuta, Ryoichi Nakamura, Tetsuya Akiyama, Shinji Hadano, Masashi Aoki, Hideyuki Saya, Gen Sobue, Hideyuki Okano;
Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent.
Nat. Med. 24:1579-1589(2018)

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Toru Okubo, Ryuhei Hayashi, Shun Shibata, Yuji Kudo, Yuki Ishikawa, Saki Inoue, Yuki Kobayashi, Ai Honda, Yoichi Honma, Satoshi Kawasaki, Kohji Nishida;
Generation and validation of a PITX2-EGFP reporter line of human induced pluripotent stem cells enables isolation of periocular mesenchymal cells.
J. Biol. Chem. 295:3456-3465(2020)

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Carol Xiu-Qing Chen, Narges Abdian, Gilles Maussion, Rhalena A. Thomas, Iveta Demirova, Eddie Cai, Mahdieh Tabatabaei, Lenore K. Beitel, Jason Karamchandani, Edward A. Fon, Thomas M. Durcan;
A multistep workflow to evaluate newly generated iPSCs and their ability to generate different cell types.
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