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A novel efficient feeder-free culture system for the derivation of human induced pluripotent stem cells.
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The use of induced pluripotent stem cells to reveal pathogenic gene mutations and explore treatments for retinitis pigmentosa.
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CHARGE syndrome modeling using patient-iPSCs reveals defective migration of neural crest cells harboring CHD7 mutations.
eLife 6:e21114.1-e21114.26(2017)

PubMed=28587749; DOI=10.1016/j.jaci.2017.04.013
Takada S., Kambe N., Kawasaki Y., Niwa A., Honda-Ozaki F., Kobayashi K., Osawa M., Nagahashi A., Semi K., Hotta A., Asaka I., Yamada Y., Nishikomori R., Heike T., Matsue H., Nakahata T., Saito M.K.
Pluripotent stem cell models of Blau syndrome reveal an IFN-gamma-dependent inflammatory response in macrophages.
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Fujimori K., Ishikawa M., Otomo A., Atsuta N., Nakamura R., Akiyama T., Hadano S., Aoki M., Saya H., Sobue G., Okano H.
Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent.
Nat. Med. 24:1579-1589(2018)

PubMed=32034090; DOI=10.1074/jbc.RA119.010713
Okubo T., Hayashi R., Shibata S., Kudo Y., Ishikawa Y., Inoue S., Kobayashi Y., Honda A., Honma Y., Kawasaki S., Nishida K.
Generation and validation of a PITX2-EGFP reporter line of human induced pluripotent stem cells enables isolation of periocular mesenchymal cells.
J. Biol. Chem. 295:3456-3465(2020)

PubMed=34287353; DOI=10.3390/mps4030050
Chen C.X.-Q., Abdian N., Maussion G., Thomas R.A., Demirova I., Cai E., Tabatabaei M., Beitel L.K., Karamchandani J., Fon E.A., Durcan T.M.
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